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  1. Article

    Open Access

    Claudin1 decrease induced by 1,25-dihydroxy-vitamin D3 potentiates gefitinib resistance therapy through inhibiting AKT activation-mediated cancer stem-like properties in NSCLC cells

    Claudins, the integral tight junction proteins that regulate paracellular permeability and cell polarity, are frequently dysregulated in cancer; however, their roles in regulating EGFR tyrosine kinase inhibito...

    Zhirong Jia, Kaiwei Wang, Yalei Duan, Kaiyong Hu, Yameng Zhang… in Cell Death Discovery (2022)

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  2. Article

    Open Access

    HPV16 E6 gene polymorphisms and the functions of the mutation site in cervical cancer among Uygur ethnic and Han nationality women in **njiang, China

    To investigate the genotype distribution of human papillomavirus (HPV) in infected Uygur and Han women in **njiang, China; analyze the HPV16 E6 gene polymorphism site and relationship with the development of c...

    Huizhen **n, Zhenzhen Pan, **angyi Zhe, Chunhe Zhang… in Cancer Cell International (2022)

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  3. Article

    Open Access

    1,25-dihydroxyvitamin D3 signaling-induced decreases in IRX4 inhibits NANOG-mediated cancer stem-like properties and gefitinib resistance in NSCLC cells

    Recent studies have demonstrated that acquisition of cancer stem-like properties plays an essential role in promoting epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKIs) resistance in non-s...

    Zhirong Jia, Yameng Zhang, Aiwen Yan, Meisa Wang, Qiushuang Han… in Cell Death & Disease (2020)

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  4. Article

    Open Access

    CD90 serves as differential modulator of subcutaneous and visceral adipose-derived stem cells by regulating AKT activation that influences adipose tissue and metabolic homeostasis

    White adipose tissue includes subcutaneous and visceral adipose tissue (SAT and VAT) with different metabolic features. SAT protects from metabolic disorders, while VAT promotes them. The proliferative and adi...

    Zhenzhen Pan, Zixin Zhou, Huiying Zhang, Hui Zhao… in Stem Cell Research & Therapy (2019)

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  5. Article

    Open Access

    Genetic variations in E6, E7 and the long control region of human papillomavirus type 16 among patients with cervical lesions in **njiang, China

    **njiang is one of the areas with the highest incidence of cervical cancer in China. Genetic variation in Human papillomavirus type 16 (HPV16) may increase the ability of the virus to mediate carcinogenesis an...

    **angyi Zhe, Huizhen **n, Zhenzhen Pan, Fuyuan **… in Cancer Cell International (2019)

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  6. Article

    Open Access

    MiR-544 promotes immune escape through downregulation of NCR1/NKp46 via targeting RUNX3 in liver cancer

    To study the potential role of miR-544 in the immune escape mechanism of hepatoma cells.

    Chenwei Pan, Luxia **ang, Zhenzhen Pan, **aodong Wang, Jie Li… in Cancer Cell International (2018)

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