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  1. Article

    Open Access

    An oligonucleotide synthesizer based on a microreactor chip and an inkjet printer

    Synthetic oligonucleotides (oligos) are important tools in the fields of molecular biology and genetic engineering. For applications requiring a large number of oligos with high concentration, it is critical t...

    Hui Li, Ye Huang, Zewen Wei, Wei Wang, Zhenjun Yang, Zicai Liang in Scientific Reports (2019)

  2. Article

    Open Access

    Tripole-mode and quadrupole-mode solitons in (1 + 1)-dimensional nonlinear media with a spatial exponential-decay nonlocality

    The approximate analytical expressions of tripole-mode and quadrupole-mode solitons in (1 + 1)-dimensional nematic liquid crystals are obtained by applying the variational approach. It is found that the solito...

    Zhi** Dai, Zhenjun Yang, **aohui Ling, Shumin Zhang, Zhaoguang Pang in Scientific Reports (2017)

  3. Article

    Open Access

    Polarization domain wall pulses in a microfiber-based topological insulator fiber laser

    Topological insulators (TIs), are novel two-dimension materials, which can act as effective saturable absorbers (SAs) in a fiber laser. Moreover, based on the evanescent wave interaction, deposition of the TI ...

    **gmin Liu, **ngliang Li, Shumin Zhang, Han Zhang, Peiguang Yan in Scientific Reports (2016)

  4. Article

    Open Access

    Bioactivity of 2′-deoxyinosine-incorporated aptamer AS1411

    Aptamers can be chemically modified to enhance nuclease resistance and increase target affinity. In this study, we performed chemical modification of 2′-deoxyinosine in AS1411, an anti-proliferative G-rich oli...

    **nmeng Fan, Lidan Sun, Yun Wu, Lihe Zhang, Zhenjun Yang in Scientific Reports (2016)

  5. Article

    Open Access

    Differential TGFβ pathway targeting by miR-122 in humans and mice affects liver cancer metastasis

    Downregulation of a predominantly hepatocyte-specific miR-122 is associated with human liver cancer metastasis, whereas miR-122-deficient mice display normal liver function. Here we show a functional conservat...

    Shenyi Yin, Yu Fan, Hanshuo Zhang, Zhihua Zhao, Yang Hao, Juan Li in Nature Communications (2016)

  6. Article

    Open Access

    Diminished serum repetin levels in patients with schizophrenia and bipolar disorder

    Repetin (RPTN) protein is a member of S100 family and is known to be expressed in the normal epidermis. Here we show that RPTN is ubiquitously expressed in both mouse and human brain, with relatively high leve...

    Shuai Wang, Huixun Ren, Jie Xu, Yanjun Yu, Shui** Han, Hui Qiao in Scientific Reports (2015)