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Article
Open AccessIntravenous infusion of small umbilical cord mesenchymal stem cells could enhance safety and delay retinal degeneration in RCS rats
Human umbilical cord mesenchymal stem cells (UCMSCs) transplantation is a promising therapy for the treatment of retinitis pigmentosa (RP). However, intravenously infused cells may be blocked in the lung, incr...
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Chapter
Usher Syndrome in Chinese and Japanese Population
Usher syndrome (USH) is the most common cause of combined blindness and deafness inherited in an autosomal recessive mode. It is clinically and genetically heterogeneous and is the most common cause underlying...
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Article
The characterization of functional disturbances in Chinese patients with Bietti’s crystalline dystrophy at different fundus stages
The aim of this study was to characterize the functional and clinical disturbances and screen the optimal functional tests in assessing Bietti’s crystalline dystrophy (BCD) patients by a cross-sectional method.
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Article
Temporal and spatial characteristics of cone degeneration in RCS rats
The temporal and spatial characteristics of cone degeneration in the Royal College of Surgeons (RCS) rat were studied to provide information for treatment strategies of retinitis pigmentosa.
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Chapter
Activation of Müller Cells Occurs During Retinal Degeneration in RCS Rats
Müller cells can be activated and included in different functions under many kinds of pathological conditions, however, the status of Müller cells in retinitis pigmentosa are still unknown. Using immunohistoch...
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Chapter
BDNF Improves the Efficacy ERG Amplitude Maintenance by Transplantation of Retinal Stem Cells in RCS Rats
The aim of this study was to evaluate the efficacy of subretinal transplantation of rat retinal stem cell when combined with Brain-derived neurotrophic factor (BDNF) in a rat model of retinal degeneration – Ro...
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Chapter
Prevalence and Risk Factors for Age-Related Macular Degeneration in China