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  1. Article

    Open Access

    Neoadjuvant camrelizumab plus nab-paclitaxel and epirubicin in early triple-negative breast cancer: a single-arm phase II trial

    Immunotherapy combined with chemotherapy has been demonstrated to be effective in early triple-negative breast cancer (TNBC). In this single-arm, phase II study with Simon’s two-stage design, we investigated t...

    Chengzheng Wang, Zhenzhen Liu, **uchun Chen, Jianghua Qiao… in Nature Communications (2023)

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  2. Article

    Open Access

    Dalpiciclib and pyrotinib in women with HER2-positive advanced breast cancer: a single-arm phase II trial

    CDK4/6 inhibitors have shown a synergistic effect with anti-HER2 therapy in hormone receptor (HR)-positive and HER2-positive breast cancer (BC). In this phase 2 study (NCT04293276), we aim to evaluate a dual-o...

    Min Yan, Limin Niu, Huimin Lv, Mengwei Zhang, **g Wang… in Nature Communications (2023)

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  3. Article

    Open Access

    Restin suppressed epithelial-mesenchymal transition and tumor metastasis in breast cancer cells through upregulating mir-200a/b expression via association with p73

    Restin belongs to MAGE superfamily and is known as MAGE H1. Restin was firstly cloned from HL-60 cells treated with all-trans retinoic acid (ATRA). Previous studies showed a pro-apoptotic role of Restin in sev...

    Zhenduo Lu, Dechuang Jiao, Jianghua Qiao, Sen Yang, Min Yan, Shude Cui… in Molecular Cancer (2015)

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