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CRL3–SPOP ubiquitin ligase complex suppresses the growth of diffuse large B-cell lymphoma by negatively regulating the MyD88/NF-κB signaling

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  1. Article

    Open Access

    lncRNA JPX/miR-33a-5p/Twist1 axis regulates tumorigenesis and metastasis of lung cancer by activating Wnt/β-catenin signaling

    MicroRNAs (miRNAs) and Twist1-induced epithelial-mesenchymal transition (EMT) in cancer cell dissemination are well established, but the involvement of long noncoding RNAs (lncRNAs) in Twist1-mediated signalin...

    **chang Pan, Shuai Fang, Haihua Tian, Chengwei Zhou, **aodong Zhao in Molecular Cancer (2020)

  2. Article

    Open Access

    Phosphorylation by mTORC1 stablizes Skp2 and regulates its oncogenic function in gastric cancer

    Both mTOR and Skp2 play critical roles in gastric cancer (GC) tumorigenesis. However, potential mechanisms for the association between these two proteins remains unidentified.

    Qirong Geng, Jianjun Liu, Zhaohui Gong, Shangxiang Chen, Shuai Chen in Molecular Cancer (2017)