-
Article
Open AccessDe novo genome assembly depicts the immune genomic characteristics of cattle
Immunogenomic loci remain poorly understood because of their genetic complexity and size. Here, we report the de novo assembly of a cattle genome and provide a detailed annotation of the immunogenomic loci. Th...
-
Article
Imbalance in the estrogen/androgen ratio may affect prostate fibrosis through the TGF-β/Smad signaling pathway
The present study aimed to investigate the effects of an imbalance in the estrogen/androgen ratio on prostate fibrosis.
-
Article
Metabolism, pharmacokinetics, and hepatic disposition of xanthones and saponins on Zhimu treatments for exploratively interpreting the discrepancy between the herbal safety and timosaponin A3-induced hepatotoxicity
Timosaponin A3, a saponin in Zhimu, elicited hepatotoxicity via oxidative stress. However, the clinical medication of Zhimu has been historically regarded as safe, probably associated with the antioxidants it con...
-
Article
Chinese medicine CGA formula ameliorates DMN-induced liver fibrosis in rats via inhibiting MMP2/9, TIMP1/2 and the TGF-β/Smad signaling pathways
Chinese medicine CGA formula consists of polysaccharide from Cordyceps sinensis mycelia (CS-PS), gypenosides and amygdalin, which is derived from Fuzheng Huayu (FZHY) capsule for treating liver fibrosis. In this ...
-
Article
Efficacy and safety of combining pentoxifylline with angiotensin-converting enzyme inhibitor or angiotensin II receptor blocker in diabetic nephropathy: a meta-analysis
Pentoxifylline (PTF) has anti-inflammatory properties, which may be beneficial for diabetic nephropathy (DN). A meta-analysis was conducted to assess the additive effect of pentoxifylline and its safety among ...
-
Article
Expression of SOCSs in human prostate cancer and their association in prognosis
Suppressors of cytokine signaling (SOCS) proteins have been identified as negative feedback regulators of cytokine-mediated signaling in various tissues, and demonstrated to play critical roles in tumorigenesi...
-
Article
Reply to the comments of Sudhir Khanna to the article: Holmium laser division of the suture causing entrapment of a drainage tube after laparoscopic nephrectomy
-
Article
Holmium laser division of a suture causing entrapment of a drainage tube after laparoscopic nephrectomy
Inability to remove a drainage tube is an uncommon complication after laparoscopic nephrectomy. We describe removal of a drainage tube that was entrapped by an abdominal wall suture. The procedure was safely p...
-
Article
Synthesis and Characterization of Transition Metal Methanesulfonates and their Catalytic Behavior in Biginelli Reactions
A series of transition metal methanesulfonates were prepared and characterized by FTIR and TG. Characteristic peaks for the methyl and sulfonyl groups were observed in the i.r. spectra. The number of crystal w...
-
Article
Benzene Adsorption in Microporous Materials
The adsorption behaviour of benzene in silicalite-1, AlPO4-5 and EU-1 has been investigated using gravimetric techniques and molecular simulation methods. For the one-dimensional, 12-membered ring (MR) channels o...
