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Preclinical study and first-in-human imaging of [18F]FAP-2286, and comparison with 2-[18F]FDG PET/CT in various cancer patients

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  1. Article

    Open Access

    Phenotypic and genetic analysis of children with unexplained neurodevelopmental delay and neurodevelopmental comorbidities in a Chinese cohort using trio-based whole-exome sequencing

    Trio-based whole-exome sequencing (trio-WES) enables identification of pathogenic variants, including copy-number variants (CNVs), in children with unexplained neurodevelopmental delay (NDD) and neurodevelopme...

    Ruohao Wu, **aojuan Li, Zhe Meng, **gan Li in Orphanet Journal of Rare Diseases (2024)

  2. Article

    Open Access

    Demystifying COVID-19 mortality causes with interpretable data mining

    While COVID-19 becomes periodical, old individuals remain vulnerable to severe disease with high mortality. Although there have been some studies on revealing different risk factors affecting the death of COVI...

    **nyu Qian, Zhihong Zuo, Danni Xu, Shanyun He, Conghao Zhou in Scientific Reports (2024)

  3. Article

    Open Access

    Assessment of water enema PET/CT: an effective imaging technique for the diagnosis of incidental colorectal 18F-FDG uptake

    To validate the feasibility of water enema PET/CT (WE-PET/CT) in incidental colorectal 18F-FDG uptake and improve the accuracy of diagnosing colorectal neoplastic lesions.

    Rongqin Zhang, Meilinuer Abudurexiti, Wanglin Qiu, Pinbo Huang in BMC Medical Imaging (2024)

  4. Article

    Open Access

    MCM10, a potential diagnostic, immunological, and prognostic biomarker in pan-cancer

    Microchromosome maintenance (MCM) proteins are a number of nuclear proteins with significant roles in the development of cancer by influencing the process of cellular DNA replication. Of the MCM protein family...

    Dengwang Chen, Na Zhong, Zhanwen Guo, Qinglu Ji, Zixuan Dong in Scientific Reports (2023)

  5. Article

    Open Access

    Retrosynthetic planning with experience-guided Monte Carlo tree search

    In retrosynthetic planning, the huge number of possible routes to synthesize a complex molecule using simple building blocks leads to a combinatorial explosion of possibilities. Even experienced chemists often...

    Siqi Hong, Hankz Hankui Zhuo, Kebing **, Guang Shao in Communications Chemistry (2023)

  6. Article

    Capacity pooling games in crowdsourcing services

    In crowdsourcing services, employers often post some complex (or difficult) tasks that individual workers cannot complete independently. In this paper, we investigate that a group of independent workers willin...

    Zhanwen Shi, Erbao Cao, Kai Nie in Electronic Commerce Research (2023)

  7. Article

    Open Access

    SARS-CoV-2 N protein enhances the anti-apoptotic activity of MCL-1 to promote viral replication

    Viral infection in respiratory tract usually leads to cell death, impairing respiratory function to cause severe disease. However, the diversity of clinical manifestations of SARS-CoV-2 infection increases the...

    Pan Pan, Weiwei Ge, Zhiwei Lei, Wei luo in Signal Transduction and Targeted Therapy (2023)

  8. Article

    Open Access

    Clinical significance of nonerythrocytic spectrin Beta 1 (SPTBN1) in human kidney renal clear cell carcinoma and uveal melanoma: a study based on Pan-Cancer Analysis

    Nonerythrocytic spectrin beta 1 (SPTBN1) is an important cytoskeletal protein that involves in normal cell growth and development via regulating TGFβ/Smad signaling pathway, and is aberrantly expressed in vari...

    Wenting Tang, Qiong Shao, Zhanwen He, Xu Zhang, **aojuan Li, Ruohao Wu in BMC Cancer (2023)

  9. Article

    Open Access

    Study on grid inefficiency for mesh-type Frisch-grid ionization chambers

    In this study, the grid inefficiency \(\sigma \) σ for a mesh-type Frisch-g...

    Changqi Liu, Hang Zhang, **aohou Bai, Jian** Zhou in The European Physical Journal C (2022)

  10. Article

    Open Access

    Identification and validation of a novel 16-gene prognostic signature for patients with breast cancer

    Despite increased early diagnosis and improved treatment in breast cancer (BRCA) patients, prognosis prediction is still a challenging task due to the disease heterogeneity. This study was to identify a novel ...

    Zhenhua Zhong, Wenqiang Jiang, **g Zhang, Zhanwen Li, Fengfeng Fan in Scientific Reports (2022)

  11. Article

    Retraction Note: Patients with ankylosing spondylitis treatment by golimumab: a systematic review and meta‑analysis

    Jami Sayed Abdulla, Jiandang Shi, Brotendu Shekhar Roy in European Spine Journal (2022)

  12. Article

    Open Access

    MiR-106b-5p regulates esophageal squamous cell carcinoma progression by binding to HPGD

    Several studies have documented the key role of microRNAs (miRNAs) in esophageal squamous cell carcinoma (ESCC). Although the expression of the 15-hydroxyprostaglandin dehydrogenase (HPGD) gene and miR-106b-5p ar...

    Fan Yang, Zhanwen Sun, Dengyun Wang, Tian Du in BMC Cancer (2022)

  13. Article

    RETRACTED ARTICLE: Osteotomy in lateral position for correcting severe thoracolumbar kyphosis combined with hip flexion contracture in ankylosing spondylitis: a case report and literature review

    Sayed Abdulla Jami, Zhanwen Zhou, Siam Al Mobarak in European Spine Journal (2021)

  14. Article

    Open Access

    Effect of cyclic wetting–drying on tensile mechanical behavior and microstructure of clay-bearing sandstone

    The understanding of the weakening mechanism of tensile strength of rock subjected to cyclic wetting-drying is critical for rock engineering. Tensile strength tests were conducted on a total of 35 sandstone sp...

    **ye Guo, Juan Gu, Yi Su, Jiong Wang in International Journal of Coal Science & Te… (2021)

  15. Article

    Open Access

    Fish bone-derived interconnected carbon nanofibers for efficient and lightweight microwave absorption

    In this work, we demonstrated a simple method for preparing three-dimensional interconnected carbon nanofibers (ICNF) derived from fish bone as an efficient and lightweight microwave absorber. The as-obtained ...

    Yangyang Gu, Peng Dai, Wen Zhang, Zhanwen Su in SN Applied Sciences (2021)

  16. Article

    LAMOST’s view on the Gaia-Sausage-Enceladus merger event

    ZhanWen Han in Science China Physics, Mechanics & Astronomy (2021)

  17. Article

    Open Access

    Variation of rhizosphere microbial community in continuous mono-maize seed production

    Soil microbe is crucial to a healthy soil, therefore its diversities and abundances under different conditions are still need fully understand.The aims of the study were to characterize the community structure...

    Yunchen Zhao, Wenjiang Fu, Changwei Hu, Guangquan Chen, Zhanwen **ao in Scientific Reports (2021)

  18. Article

    Open Access

    Heterotrimeric G-protein α subunit (LeGPA1) confers cold stress tolerance to processing tomato plants (Lycopersicon esculentum Mill)

    Tomatoes (Lycopersicon esculentum Mill) are key foods, and their molecular biology and evolution have been well described. Tomato plants originated in the tropics and, thus, are cold sensitive.

    **nyong Guo, Juju Li, Li Zhang, Zhanwen Zhang, ** He, Wenwen Wang in BMC Plant Biology (2020)

  19. Article

    Open Access

    Diagnostic performance of ultrasonography, dual-phase 99mTc-MIBI scintigraphy, early and delayed 99mTc-MIBI SPECT/CT in preoperative parathyroid gland localization in secondary hyperparathyroidism

    Secondary hyperparathyroidism (SHPT) usually requires parathyroidectomy when drug regimens fail. However, obtaining an exact preoperative map of the locations of the parathyroid glands is a challenge. The purp...

    Rongqin Zhang, Zhanwen Zhang, Pinbo Huang, Zhi Li, Rui Hu, Jie Zhang in BMC Medical Imaging (2020)

  20. Article

    Open Access

    Eravacycline susceptibility was impacted by genetic mutation of 30S ribosome subunits, and branched-chain amino acid transport system II carrier protein, Na/Pi cotransporter family protein in Staphylococcus aureus

    Our previous research indicated the excellent in vitro antibacterial activity of Eravacycline (Erava) and its heteroresistance frequency against clinical Staphylococcus aureus isolates. In this study, we further ...

    Zhanwen Wang, Zhiwei Lin, Bing Bai, Guangjian Xu, Peiyu Li, Zhijian Yu in BMC Microbiology (2020)

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