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  1. Article

    Open Access

    Metabolomic and transcriptomic analyses of peach leaves and fruits in response to pruning

    Pruning is an important cultivation management option that has important effects on peach yield and quality. However, the effects of pruning on the overall genetic and metabolic changes in peach leaves and fru...

    **ao-Fei Liu, **u-Hong An, **n-Miao Li, He Zhang, Hong-Bo Cao in BMC Genomics (2024)

  2. Article

    Open Access

    Comparative transcriptome and DNA methylation analysis in temperature-sensitive genic male sterile wheat BS366

    Known as the prerequisite component for the heterosis breeding system, the male sterile line determines the hybrid yield and seed purity. Therefore, a deep understanding of the mechanism and gene network that ...

    Yong-jie Liu, Dan Li, Jie Gong, Yong-bo Wang, Zhao-bo Chen, Bin-shuang Pang in BMC Genomics (2021)

  3. Article

    Open Access

    Genome-wide identification and transcriptional characterization of DNA methyltransferases conferring temperature-sensitive male sterility in wheat

    DNA methyltransferase (DMT) genes contribute to plant stress responses and development by de novo establishment and subsequent maintenance of DNA methylation during replication. The photoperiod and/or temperat...

    Dan Li, Bian-E Feng, Yong-Jie Liu, Jie Gong, Yi-Miao Tang, Li-** Zhang in BMC Genomics (2021)

  4. Article

    Open Access

    Transcriptomic analysis of α-linolenic acid content and biosynthesis in Paeonia ostii fruits and seeds

    Paeonia ostii is a potentially important oilseed crop because its seed yield is high, and the seeds are rich in α-linolenic acid (ALA). However, the molecular mechanisms underlying ALA biosynthesis during seed ke...

    Shui-Yan Yu, **ao Zhang, Liang-Bo Huang, Yu-** Lyu, Ying Zhang in BMC Genomics (2021)

  5. Article

    Open Access

    A statistical measure for the skewness of X chromosome inactivation based on case-control design

    Skewed X chromosome inactivation (XCI), which is a non-random process, is frequently observed in both healthy and affected females. Furthermore, skewed XCI has been reported to be related to many X-linked dise...

    Peng Wang, Yu Zhang, Bei-Qi Wang, Jian-Long Li, Yi-**n Wang in BMC Bioinformatics (2019)

  6. Article

    Open Access

    BMCMDA: a novel model for predicting human microbe-disease associations via binary matrix completion

    Human Microbiome Project reveals the significant mutualistic influence between human body and microbes living in it. Such an influence lead to an interesting phenomenon that many noninfectious diseases are clo...

    Jian-Yu Shi, Hua Huang, Yan-Ning Zhang, Jiang-Bo Cao, Siu-Ming Yiu in BMC Bioinformatics (2018)

  7. Article

    Open Access

    Large scale tissue histopathology image classification, segmentation, and visualization via deep convolutional activation features

    Histopathology image analysis is a gold standard for cancer recognition and diagnosis. Automatic analysis of histopathology images can help pathologists diagnose tumor and cancer subtypes, alleviating the work...

    Yan Xu, Zhipeng Jia, Liang-Bo Wang, Yuqing Ai, Fang Zhang, Maode Lai in BMC Bioinformatics (2017)

  8. Article

    Open Access

    DisBind: A database of classified functional binding sites in disordered and structured regions of intrinsically disordered proteins

    Intrinsically unstructured or disordered proteins function via interacting with other molecules. Annotation of these binding sites is the first step for map** functional impact of genetic variants in coding ...

    Jia-Feng Yu, **ang-Hua Dou, Yu-Jie Sha, Chun-Ling Wang, Hong-Bo Wang in BMC Bioinformatics (2017)

  9. Article

    Open Access

    Comparative genomic analysis identifies structural features of CRISPR-Cas systems in Riemerella anatipestifer

    Riemerella anatipestifer infection is a contagious disease that has resulted in major economic losses in the duck industry worldwide. This study attempted to characterize CRISPR-Cas sy...

    De-Kang Zhu, Xue-Qin Yang, Yang He, Wang-Shu Zhou, **ao-Heng Song in BMC Genomics (2016)

  10. Article

    Open Access

    Exploration of microRNAs in porcine milk exosomes

    Breast milk contains complex nutrients and facilitates the maturation of various biological systems in infants. Exosomes, membranous vesicles of endocytic origin found in different body fluids such as milk, ca...

    Ting Chen, Qian-Yun **, Rui-Song Ye, **ao Cheng, Qi-En Qi, Song-Bo Wang in BMC Genomics (2014)

  11. Article

    Open Access

    De novo characterization of a whitefly transcriptome and analysis of its gene expression during development

    Whitefly (Bemisia tabaci) causes extensive crop damage throughout the world by feeding directly on plants and by vectoring hundreds of species of begomoviruses. Yet little is understood about its genes involved i...

    **ao-Wei Wang, Jun-Bo Luan, Jun-Min Li, Yan-Yuan Bao, Chuan-** Zhang in BMC Genomics (2010)