-
Article
Open AccessMetabolomic and transcriptomic analyses of peach leaves and fruits in response to pruning
Pruning is an important cultivation management option that has important effects on peach yield and quality. However, the effects of pruning on the overall genetic and metabolic changes in peach leaves and fru...
-
Article
Open AccessComparative transcriptome and DNA methylation analysis in temperature-sensitive genic male sterile wheat BS366
Known as the prerequisite component for the heterosis breeding system, the male sterile line determines the hybrid yield and seed purity. Therefore, a deep understanding of the mechanism and gene network that ...
-
Article
Open AccessGenome-wide identification and transcriptional characterization of DNA methyltransferases conferring temperature-sensitive male sterility in wheat
DNA methyltransferase (DMT) genes contribute to plant stress responses and development by de novo establishment and subsequent maintenance of DNA methylation during replication. The photoperiod and/or temperat...
-
Article
Open AccessTranscriptomic analysis of α-linolenic acid content and biosynthesis in Paeonia ostii fruits and seeds
Paeonia ostii is a potentially important oilseed crop because its seed yield is high, and the seeds are rich in α-linolenic acid (ALA). However, the molecular mechanisms underlying ALA biosynthesis during seed ke...
-
Article
Open AccessA statistical measure for the skewness of X chromosome inactivation based on case-control design
Skewed X chromosome inactivation (XCI), which is a non-random process, is frequently observed in both healthy and affected females. Furthermore, skewed XCI has been reported to be related to many X-linked dise...
-
Article
Open AccessBMCMDA: a novel model for predicting human microbe-disease associations via binary matrix completion
Human Microbiome Project reveals the significant mutualistic influence between human body and microbes living in it. Such an influence lead to an interesting phenomenon that many noninfectious diseases are clo...
-
Article
Open AccessLarge scale tissue histopathology image classification, segmentation, and visualization via deep convolutional activation features
Histopathology image analysis is a gold standard for cancer recognition and diagnosis. Automatic analysis of histopathology images can help pathologists diagnose tumor and cancer subtypes, alleviating the work...
-
Article
Open AccessDisBind: A database of classified functional binding sites in disordered and structured regions of intrinsically disordered proteins
Intrinsically unstructured or disordered proteins function via interacting with other molecules. Annotation of these binding sites is the first step for map** functional impact of genetic variants in coding ...
-
Article
Open AccessComparative genomic analysis identifies structural features of CRISPR-Cas systems in Riemerella anatipestifer
Riemerella anatipestifer infection is a contagious disease that has resulted in major economic losses in the duck industry worldwide. This study attempted to characterize CRISPR-Cas sy...
-
Article
Open AccessExploration of microRNAs in porcine milk exosomes
Breast milk contains complex nutrients and facilitates the maturation of various biological systems in infants. Exosomes, membranous vesicles of endocytic origin found in different body fluids such as milk, ca...
-
Article
Open AccessDe novo characterization of a whitefly transcriptome and analysis of its gene expression during development
Whitefly (Bemisia tabaci) causes extensive crop damage throughout the world by feeding directly on plants and by vectoring hundreds of species of begomoviruses. Yet little is understood about its genes involved i...