-
Article
Open AccessAdvancing Guideline-Directed Medical Therapy in Heart Failure: Overcoming Challenges and Maximizing Benefits
The delayed titration of guideline-directed drug therapy (GDMT) is a complex event influenced by multiple factors that often result in poor prognosis for patients with heart failure (HF). Individualized adjust...
-
Article
Open AccessHuman periodontal ligament stem cell sheets activated by graphene oxide quantum dots repair periodontal bone defects by promoting mitochondrial dynamics dependent osteogenic differentiation
Bone defects in the maxillofacial region restrict the integrity of dental function, posing challenges in clinical treatment. Bone tissue engineering (BTE) with stem cell implants is an effective method. Nanobi...
-
Article
One droplet reaction for synthesis of multi-sized nanoparticles
Reaction kinetics of nanoparticles can be controlled by tuning the Peclet number (Pe) as it is an essential parameter in synthesis of multi-sized nanoparticles. Herein, we propose to implement a self-driven multi...
-
Article
The role of p21-activated kinase 4 in the progression of oral squamous cell carcinoma by targeting PI3K–AKT signaling pathway
Oral squamous carcinoma (OSCC), the most common head and neck malignancy, has a strong propensity for malignant proliferation and metastasis, which will decrease the survival of patients. P21-activated kinase ...
-
Article
Transpiration-inspired Capillary for Synchronous Synthesis and Patterning of Silver Nanoparticles
Traditional synthesis strategy of nanomaterials with complicated process and high cost limits their applications. Here, we propose a facile process for the synchronous synthesis and patterning of silver nanopar.....
-
Article
Open AccessSign-reversible valley-dependent Berry phase effects in 2D valley-half-semiconductors
Manipulating valley-dependent Berry phase effects provides remarkable opportunities for both fundamental research and practical applications. Here, by referring to effective model analysis, we propose a genera...
-
Article
Simvastatin inhibits oral squamous cell carcinoma by targeting TMEM16A Ca2+-activated chloride channel
Ca2+-activated chloride channel TMEM16A has been found to be overexpressed in many cancers including head and neck squamous cell carcinoma (HNSCC). Nevertheless, the role of TMEM16A in oral squamous cell carcinom...
-
Article
Open AccessCrizotinib in patients with anaplastic lymphoma kinase-positive advanced non-small cell lung cancer versus chemotherapy as a first-line treatment
To compare the efficacy of crizotinib, pemetrexed and other chemotherapy regimens as a first-line treatment in patients with anaplastic lymphoma kinase (ALK)-positive non-small cell lung cancer (NSCLC) in real...
-
Article
High-level production of α-amylase by manipulating the expression of alanine racamase in Bacillus licheniformis
To improve target protein production by manipulating expression levels of alanine racemase in Bacillus licheniformis.
-
Chapter and Conference Paper
Characteristics and Enlightenment of Faculty Building for Vocational Education in Developed Countries
Faculty is undoubtedly a key factor in the success of vocational education. The experience of faculty building for vocational education in developed countries enlightens the faculty building for vocational col...
