30 Result(s)
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Zengjun **
Biomedicine
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Article
Open AccessSPTBN1 abrogates renal clear cell carcinoma progression via glycolysis reprogramming in a GPT2-dependent manner
Renal clear cell carcinoma (ccRCC) is the most prevalent tumors worldwide. Discovering effective biomarkers is essential to monitor the prognosis and provide alternative clinical options. SPTBN1 is implicated ...
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Open AccessThe long non-coding RNA LNC_000397 negatively regulates PRRSV replication through induction of interferon-stimulated genes
Porcine reproductive and respiratory syndrome virus (PRRSV) is one of the most significant threats to the global swine industry. It is of great importance to understand viral-host interactions to develop novel...
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Open AccessPrognostic value and immunological role of AXL gene in clear cell renal cell carcinoma associated with identifying LncRNA/RBP/AXL mRNA networks
This article aimed to explore the prognostic and immunological roles of AXL gene in clear cell renal cell carcinoma (ccRCC) for overall survival (OS) and to identify the LncRNA/RBP/AXL mRNA networks.
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The rescue and selection of thermally stable type O vaccine candidate strains of foot-and-mouth disease virus
Inactivated foot-and-mouth disease virus (FMDV) vaccines have been used widely to control foot-and-mouth disease (FMD). However, the virions (146S) of this virus are easily dissociated into pentamer subunits (...
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Open AccessTRIM37 orchestrates renal cell carcinoma progression via histone H2A ubiquitination-dependent manner
Ubiquitylation modification is one of the multiple post-transcriptional process to regulate cellular physiology, including cell signaling, cycle regulation, DNA repair and transcriptional regulation. Members o...
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Open AccessHigh expression of CDCA7 predicts poor prognosis for clear cell renal cell carcinoma and explores its associations with immunity
Cell division cycle-associated 7 (CDCA7), as a member of the cell division cycle associated family, was reported to be aberrantly expressed in both solid tumors and hematological tumors, suggesting its essenti...
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Open AccessRobust performance of a novel stool DNA test of methylated SDC2 for colorectal cancer detection: a multicenter clinical study
Stool DNA testing is an emerging and attractive option for colorectal cancer (CRC) screening. We previously evaluated the feasibility of a stool DNA (sDNA) test of methylated SDC2 for CRC detection. The aim of th...
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Open AccessIdentification of the largest non-essential regions of the C-terminal portion in 3A protein of foot-and-mouth disease virus for replication in cell culture
Recent study has shown that the C-terminal portion of 3A (amino acids (aa) 81–153) is not essential for foot-and-mouth disease virus replication in cell culture, however, the complete C-terminal portion (aa 77...
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Open AccessALDH1A3 serves as a predictor for castration resistance in prostate cancer patients
Aldehyde dehydrogenase 1A3 (ALDH1A3) has been implicated in the survival and proliferation of prostate cancer cells.
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Genetic variations in Hippo pathway genes influence bladder cancer risk in a Chinese population
The Hippo pathway participates in development of numerous tumors through regulating tissue growth and cell fate. This study aimed to detect the association between the genetic variants in Hippo pathway genes a...
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Altered amygdala-related structural covariance and resting-state functional connectivity in end-stage renal disease patients
Depression and cognitive control deficits were frequently reported in concurrent end-stage renal disease (ESRD) patients. Neuroimaging studies indicated depression could be a risk factor for cognitive control ...
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Abnormal interaction between cognitive control network and affective network in patients with end-stage renal disease
End-stage renal disease (ESRD) is a common complicated disorder that is generally associated with an altered central nervous system and cognitive impairment. Neuroimaging studies have recorded aberrant brain c...
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Open AccessThe pH stability of foot-and-mouth disease virus
This review summarized the molecular determinants of the acid stability of FMDV in order to explore the uncoating mechanism of FMDV and improve the acid stability of vaccines.
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Open AccessBCL-2 and MYC gain/amplification is correlated with central nervous system involvement in diffuse large B cell lymphoma at leukemic phase
Diffuse large B-cell lymphoma (DLBCL) of leukemic phase is a rare clinical manifestation, but is highly prevalent with central nervous system involvement (CNSI). Little is known about this rare clinical observ...
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Overexpression of long non-coding RNA LOC400891 promotes tumor progression and poor prognosis in prostate cancer
Tumor recurrence and metastasis remain the major obstacles for the successful treatment of patients diagnosed with prostate cancer (PCa). In recent years, long non-coding RNAs (lncRNAs) have been considered as...
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BAG3 regulates cell proliferation, migration, and invasion in human colorectal cancer
Bcl2-associated athanogene 3 (BAG3) has been reported to be elevated in various tumors. However, it is unclear whether BAG3 has a functional role in the initiation and progression of colorectal cancer (CRC). H...
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Open AccessH19-derived miR-675 contributes to bladder cancer cell proliferation by regulating p53 activation
Long noncoding RNA 19 (H19) has been shown to promote bladder cancer cell proliferation and metastasis. However, little is known about how miR-675, mature product of H19, contributes to bladder cancer cell pro...
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RETRACTED ARTICLE: Clinical significance of CUL4A in human prostate cancer
Aberrant expression of the Cullin 4A (CUL4A) is found in many tumor types, but the functions and mechanism of CUL4A in prostate cancer (PCa) development and progression remain largely unknown. The aim of this ...
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Isolation and sequence analysis of a canine distemper virus from a raccoon dog in Jilin Province, China
Canine distemper virus (CDV) is a major pathogen not only in raccoon dogs but also in a variety of carnivorous animals, including domesticated animals, particularly if they have not been vaccinated. In this st...
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Serum metabolomic analysis of human upper urinary tract urothelial carcinoma
To find potential serum biomarkers for upper tract urothelial carcinomas (UTUCs) via 1H nuclear magnetic resonance (1H NMR)-based metabolomic analysis. Serum specimens collected from 34 healthy individuals and 39...
