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  1. Article

    Open Access

    The relationship between headache-attributed disability and lost productivity: 3 Attack frequency is the dominating variable

    In an earlier paper, we examined the relationship between headache-attributed disability, measured as proportion of time in ictal state, and lost productivity. In a linear model, we found positive and signific...

    Andreas Husøy, Zaza Katsarava, Timothy J. Steiner in The Journal of Headache and Pain (2023)

  2. Article

    Open Access

    European Headache Federation (EHF) consensus on the definition of effective treatment of a migraine attack and of triptan failure

    Triptans are migraine-specific acute treatments. A well-accepted definition of triptan failure is needed in clinical practice and for research. The primary aim of the present Consensus was to provide a definit...

    Simona Sacco, Christian Lampl, Faisal Mohammad Amin in The Journal of Headache and Pain (2022)

  3. Article

    Open Access

    European Headache Federation guideline on the use of monoclonal antibodies targeting the calcitonin gene related peptide pathway for migraine prevention – 2022 update

    A previous European Headache Federation (EHF) guideline addressed the use of monoclonal antibodies targeting the calcitonin gene-related peptide (CGRP) pathway to prevent migraine. Since then, randomized contr...

    Simona Sacco, Faisal Mohammad Amin, Messoud Ashina in The Journal of Headache and Pain (2022)

  4. Article

    Open Access

    The Global Campaign turns 18: a brief review of its activities and achievements

    The Global Campaign against Headache, as a collaborative activity with the World Health Organization (WHO), was formally launched in Copenhagen in March 2004. In the month it turns 18, we review its activities...

    Timothy J. Steiner, Gretchen L. Birbeck in The Journal of Headache and Pain (2022)

  5. Article

    Open Access

    Results of the gErman migraine PatIent Survey on medical Care and prOPhylactic treatment Experience (EPISCOPE)

    Migraine affects about 12% of the worldwide population causing substantial personal and societal burden. Yet, migraine remains underdiagnosed and untreated. EPISCOPE was a web-based survey among a German migra...

    Marie Groth, Zaza Katsarava, Marc Ehrlich in Scientific Reports (2022)

  6. Article

    Open Access

    The relationship between headache-attributed disability and lost productivity: 2. Empirical evidence from population-based studies in nine disparate countries

    Headache disorders are disabling, with major consequences for productivity, yet the literature is silent on the relationship between headache-attributed disability and lost productivity, often erroneously rega...

    Hallie Thomas, Simple Futarmal Kothari, Andreas Husøy in The Journal of Headache and Pain (2021)

  7. Article

    Open Access

    Diagnosis and management of migraine in ten steps

    Migraine is a disabling primary headache disorder that directly affects more than one billion people worldwide. Despite its widespread prevalence, migraine remains under-diagnosed and under-treated. To support...

    Anna K. Eigenbrodt, Håkan Ashina, Sabrina Khan in Nature Reviews Neurology (2021)

  8. Article

    Open Access

    Structured headache services as the solution to the ill-health burden of headache: 1. Rationale and description

    In countries where headache services exist at all, their focus is usually on specialist (tertiary) care. This is clinically and economically inappropriate: most headache disorders can effectively and more effi...

    Timothy J. Steiner, Rigmor Jensen, Zaza Katsarava in The Journal of Headache and Pain (2021)

  9. Article

    Open Access

    Burden and attitude to resistant and refractory migraine: a survey from the European Headache Federation with the endorsement of the European Migraine & Headache Alliance

    New treatments are currently offering new opportunities and challenges in clinical management and research in the migraine field. There is the need of homogenous criteria to identify candidates for treatment e...

    Simona Sacco, Christian Lampl in The Journal of Headache and Pain (2021)

  10. Article

    Open Access

    The impact of fremanezumab on medication overuse in patients with chronic migraine: subgroup analysis of the HALO CM study

    We evaluated the efficacy of fremanezumab, a fully humanized monoclonal antibody that selectively targets calcitonin gene-related peptide, in patients with chronic migraine (CM) with and without medication ove...

    Stephen D. Silberstein, Joshua M. Cohen in The Journal of Headache and Pain (2020)

  11. Article

    Open Access

    Administrative prevalence and incidence, characteristics and prescription patterns of patients with migraine in Germany: a retrospective claims data analysis

    Migraine is a frequent headache disorder with high disease burden. The aims of this study were to determine the administrative prevalence and incidence of migraine in Germany; and to elucidate disease characte...

    Tatjana Roessler, Juergen Zschocke, Anne Roehrig in The Journal of Headache and Pain (2020)

  12. Article

    Open Access

    European headache federation consensus on the definition of resistant and refractory migraine

    Despite advances in the management of headache disorders, some patients with migraine do not experience adequate pain relief with acute and preventive treatments. It is the aim of the present document to provi...

    Simona Sacco, Mark Braschinsky, Anne Ducros in The Journal of Headache and Pain (2020)

  13. Article

    Open Access

    Migraine: a major debilitating chronic non-communicable disease in Brazil, evidence from two national surveys

    Even though migraine and other primary headache disorders are common and debilitating, major health surveys in Brazil have not included them. We repair this omission by combining data on non-communicable disea...

    Mario Fernando Prieto Peres, Luiz Paulo Queiroz in The Journal of Headache and Pain (2019)

  14. No Access

    Chapter

    Barriers to Care

    This chapter describes the barriers to effective headache care, high everywhere in the world, and in many places insurmountable by the majority of those needing care. It reports on the largely ineffective ende...

    Timothy J. Steiner, Zaza Katsarava, Jes Olesen in Societal Impact of Headache (2019)

  15. No Access

    Chapter

    Evaluation: Quality in Headache Services

    This chapter sets out a multidimensional definition of quality in the context of headache care, along with a related set of quality indicators currently undergoing evaluation. Both were developed for the purposes...

    Timothy J. Steiner, Rigmor Jensen, Raquel Gil-Gouveia in Societal Impact of Headache (2019)

  16. No Access

    Chapter

    The Healthcare Solution to Headache

    This chapter builds on Chap. 14, describing structured headache services as the healthcare solution to headache.

    Timothy J. Steiner, Rigmor Jensen, Zaza Katsarava in Societal Impact of Headache (2019)

  17. No Access

    Chapter

    Dismantling the Barriers

    The preceding chapter described the barriers to effective headache care, high as they are, and insurmountable for many. Dismantling them is not an easy task. The Global Campaign against Headache is a response ...

    Timothy J. Steiner, Rigmor Jensen, Paolo Martelletti in Societal Impact of Headache (2019)

  18. Article

    Open Access

    Polarity-specific modulation of pain processing by transcranial direct current stimulation – a blinded longitudinal fMRI study

    To enrich the hitherto insufficient understanding regarding the mechanisms of action of transcranial direct current stimulation (tDCS) in pain disorders, we investigated its modulating effects on cerebral pain...

    Steffen Naegel, Josephine Biermann, Nina Theysohn in The Journal of Headache and Pain (2018)

  19. Article

    Open Access

    Medication-overuse headache: a widely recognized entity amidst ongoing debate

    Medication overuse in primary headache disorders is a worldwide phenomenon and has a role in the chronification of headache disorders. The burden of disease on individuals and societies is significant due to h...

    Nicolas Vandenbussche, Domenico Laterza, Marco Lisicki in The Journal of Headache and Pain (2018)

  20. Article

    Open Access

    Poor medical care for people with migraine in Europe – evidence from the Eurolight study

    Migraine is prevalent everywhere, and disabling. It is also neglected: consequently, it is under-diagnosed and undertreated. We analysed data from the Eurolight study on consultations and utilization of migrai...

    Zaza Katsarava, Maka Mania, Christian Lampl in The Journal of Headache and Pain (2018)

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