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Article
Open AccessGlucagon-like peptide-1 receptor agonists and heart failure in type 2 diabetes: systematic review and meta-analysis of randomized and observational studies
The effect of glucagon-like peptide-1(GLP-1) receptor agonists on heart failure remains uncertain. We therefore conducted a systematic review to assess the possible impact of GLP-1 agonists on heart failure or...
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Article
Open AccessAssessing the quality of published genetic association studies in meta-analyses: the quality of genetic studies (Q-Genie) tool
Advances in genomics technology have led to a dramatic increase in the number of published genetic association studies. Systematic reviews and meta-analyses are a common method of synthesizing findings and pro...
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Article
Open AccessDoes genetic heterogeneity account for the divergent risk of type 2 diabetes in South Asian and white European populations?
South Asians are up to four times more likely to develop type 2 diabetes than white Europeans. It is postulated that the higher prevalence results from greater genetic risk. To evaluate this hypothesis, we: (1...