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Article
Sex Specific Global Burden of Osteoporosis in 204 Countries and Territories, from 1990 to 2030: An Age-Period-Cohort Modeling Study
Osteoporosis is a highly prevalent disease with distinct sex pattern. We aimed to estimate the sex specific incidence, prevalence, and disability-adjusted life (DALYs) years of osteoporosis between 1990 and 20...
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Chapter and Conference Paper
Characteristics of Excavated Waste from a 14-Year-Old Landfill Bioreactor: Calgary Biocell Case Study
In this paper, preliminary results from a characterization study of excavated waste samples from the Calgary BioCell is presented. The Calgary BioCell has operated as a landfill bioreactor for 14 years with le...
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Article
Open AccessWeight and BMI Patterns in a Biologicals-Treated IBD Cohort
Biologic therapies are effective at inducing and maintaining remission in people with inflammatory bowel disease (IBD). Previous studies have associated TNF-a inhibitors with weight gain, however, it is unclea...
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Article
Growth characteristics of acclimated strain of Chlorella vulgaris under high concentrations of ammonia nitrogen and phosphorus
Treatment and recycling of high concentrations of ammonia nitrogen (NH4+–N) and tatal phosphorus (TP) is a major challenge in today’s wastewater industry, while microalgae not only captures CO2, but also provide ...
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Article
Topology optimization for polymeric stent
The topological optimization technique is an effective way to provide the optimal design for the polymeric stents. Conventional topology optimization procedure for polymeric stent was all based on classical th...
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Article
Peripheral blood T-cell receptor repertoire as a predictor of clinical outcomes in gastrointestinal cancer patients treated with PD-1 inhibitor
Identifying valid biomarkers for patient selection impressively promotes the success of anti-PD-1 therapy. However, the unmet need for biomarkers in gastrointestinal (GI) cancers remains significant. We aimed ...
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Article
Synthesis and Properties of Dimercury(I) Crystal Network Constructed with Functionalized Pyrazine Sulfonate and Nitrate Linkers
Coordination nature in the structures between the heterocyclic sulfonic acid group and heavy metal atoms, structural optimization, their physical and chemical properties have been studied. Herein, a new compou...
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Article
Open AccessChildhood obesity prevention through a community-based cluster randomized controlled physical activity intervention among schools in china: the health legacy project of the 2nd world summer youth olympic Games (YOG-Obesity study)
Childhood obesity has been becoming a worldwide public health problem. We conducted a community-based physical activity (PA) intervention program aiming at childhood obesity prevention in general student popul...
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Article
Micropapillary bladder cancer: a clinico-pathological characterization and treatment analysis
Micropapillary bladder cancer (MPBC) is a very rare and aggressive variant of urothelial carcinoma (UC). The aim of this study was to investigate the clinico-pathological characteristics, treatment, and progno...
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Article
Open AccessHuntington’s disease cerebrospinal fluid seeds aggregation of mutant huntingtin
Huntington’s disease (HD), a progressive neurodegenerative disease, is caused by an expanded CAG triplet repeat producing a mutant huntingtin protein (mHTT) with a polyglutamine-repeat expansion. Onset of symp...
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Article
Open AccessmiRNAs in mtDNA-less cell mitochondria
The novel regulation mechanism in mtDNA-less cells was investigated. Very low mtDNA copy in mtDNA-less 206 ρ° cells was identified. But no 13 mitochondria-specific proteins were translated in 206 ρ° cells. Their ...
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Article
Failure mechanisms of concrete slab–soil double-layer structure subjected to underground explosion
The failure mechanism of a concrete slab–soil double-layer structure subjected to an underground explosion was investigated by experimental and numerical methods in this paper. Two underground explosion depths...
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Article
Open AccessTargeting Epstein–Barr virus oncoprotein LMP1-mediated glycolysis sensitizes nasopharyngeal carcinoma to radiation therapy
Our goal in this work was to illustrate the Epstein-Barr virus (EBV)-modulated global biochemical profile and provide a novel metabolism-related target to improve the therapeutic regimen of nasopharyngeal carc...
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Article
Biodistribution of 212Pb conjugated trastuzumab in mice
The biodistribution in mice of 212Pb-trastuzumab, a HER2 targeting immunoglobulin (monoclonal antibody), was investigated for its potential as a therapeutic agent with immunocytotoxic applications. 212Pb-trastuzu...
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Article
Chemically Amplified Resist Approaches for E-beam Lithography Mask Fabrication
This paper describes stable, high sensitivity (5-10 ώC/cm2 at 50 kV) e-beam resist systems utilizing chemical amplification suitable for mask fabrication for device generations below 100 nm. In particular, two re...
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Article
17β-Estradiol attenuates diet-induced insulin resistance and glucose intolerance through up-regulation of caveolin-3
Although estrogen contributes to glucose homeostasis, its mechanisms remain unclear.
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Article
Controlled reperfusion prevents neurologic injury after global brain ischemia in a novel ischemic brain model
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Article
Mutant ubiquitin found in Alzheimer's disease causes neuritic beading of mitochondria in association with neuronal degeneration
A dinucleotide deletion in human ubiquitin (Ub) B messenger RNA leads to formation of polyubiquitin (UbB)+1, which has been implicated in neuronal cell death in Alzheimer's and other neurodegenerative diseases...
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Article
Electron inelastic interactions in bioorganic compounds in the energy range of 20–10000 eV
Systematic calculations of stop** powers (SPs) and mean free paths (MFPs) for 10 bioorganic compounds have been performed for electrons with energies lower than 10 keV, based on dielectric response theory an...
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Article
An investigation of distribution parameters for fluorine ion implantation in indium-tin-oxide films
Implanted-fluorine profiles in ITO films have been accurately measured using the 19F(p,αγ)16O resonance nuclear reaction at ER=872.1 keV, with width Γ=4.2 keV. A proper deconvolution calculation method was used t...
