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  1. Article

    Open Access

    Neuroepithelial cell competition triggers loss of cellular juvenescence

    Cell competition is a cell–cell interaction mechanism which maintains tissue homeostasis through selective elimination of unfit cells. During early brain development, cells are eliminated through apoptosis. Ho...

    Faidruz Azura Jam, Takao Morimune, Atsushi Tsukamura, Ayami Tano in Scientific Reports (2020)

  2. Article

    Open Access

    TrkA inhibitor promotes motor functional regeneration of recurrent laryngeal nerve by suppression of sensory nerve regeneration

    Recurrent laryngeal nerve (RLN) injury, in which hoarseness and dysphagia arise as a result of impaired vocal fold movement, is a serious complication. Misdirected regeneration is an issue for functional regen...

    Hiroshi Suzuki, Koji Araki, Toshiyasu Matsui, Yuya Tanaka, Kosuke Uno in Scientific Reports (2020)

  3. Article

    Open Access

    Self-Assembled Electret for Vibration-Based Power Generator

    The vibration-based electret generators (EGs) for energy harvesting have been extensively studied because they can obtain electrical energy from ambient vibrations. EGs exhibit a sandwich structure of electrod...

    Yuya Tanaka, Noritaka Matsuura, Hisao Ishii in Scientific Reports (2020)

  4. No Access

    Article

    An antiaromatic-walled nanospace

    Over the past few decades, several molecular cages, hosts and nanoporous materials enclosing nanometre-sized cavities have been reported15, including coordination-driven nanocages6. Such nanocages have found wid...

    Masahiro Yamashina, Yuya Tanaka, Roy Lavendomme, Tanya K. Ronson in Nature (2019)

  5. Article

    Open Access

    In vivo epigenetic editing of Sema6a promoter reverses transcallosal dysconnectivity caused by C11orf46/Arl14ep risk gene

    Many neuropsychiatric risk genes contribute to epigenetic regulation but little is known about specific chromatin-associated mechanisms governing the formation of neuronal connectivity. Here we show that trans...

    Cyril J. Peter, Atsushi Saito, Yuto Hasegawa, Yuya Tanaka in Nature Communications (2019)

  6. Article

    Open Access

    Increased plasma VEGF levels following ischemic preconditioning are associated with downregulation of miRNA-762 and miR-3072-5p

    Ischemic preconditioning (IPC) has protective effects against ischemia-perfusion injury of organs. In the present study, we investigated the associated mechanisms after performing remote IPC (rIPC) of lower li...

    Koji Ueno, Makoto Samura, Tamami Nakamura, Yuya Tanaka in Scientific Reports (2016)

  7. Article

    Open Access

    Treatment of refractory cutaneous ulcers with mixed sheets consisting of peripheral blood mononuclear cells and fibroblasts

    The purpose of this study was to confirm the therapeutic effects of mixed sheets consisting of peripheral blood mononuclear cells (PBMNCs) and fibroblasts on cutaneous skin ulcers. Vascular endothelial growth ...

    Koji Ueno, Yuriko Takeuchi, Makoto Samura, Yuya Tanaka in Scientific Reports (2016)

  8. Article

    Open Access

    Influence of aging on the quantity and quality of human cardiac stem cells

    Advanced age affects various tissue-specific stem cells and decreases their regenerative ability. We therefore examined whether aging affected the quantity and quality of cardiac stem cells using cells obtaine...

    Tamami Nakamura, Tohru Hosoyama, Daichi Kawamura, Yuriko Takeuchi in Scientific Reports (2016)

  9. Article

    Open Access

    Combinatorial Treatment with Apelin-13 Enhances the Therapeutic Efficacy of a Preconditioned Cell-Based Therapy for Peripheral Ischemia

    Hypoxic pretreatment of peripheral blood mononuclear cells (PBMNCs) enhances therapeutic angiogenesis in ischemic tissues after cell transplantation. However, newly formed vessels generated using this approach...

    Makoto Samura, Noriyasu Morikage, Kotaro Suehiro, Yuya Tanaka in Scientific Reports (2016)