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  1. Article

    Open Access

    HIF1α-dependent hypoxia response in myeloid cells requires IRE1α

    Cellular adaptation to low oxygen tension triggers primitive pathways that ensure proper cell function. Conditions of hypoxia and low glucose are characteristic of injured tissues and hence successive waves of...

    Gaëlle Mawambo, Malika Oubaha, Yusuke Ichiyama… in Journal of Neuroinflammation (2023)

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  2. No Access

    Article

    Efficacy of scleral imbrication on all quadrants in enucleated pig eyes

    To evaluate the changes in axial length (AL) and corneal astigmatism induced by scleral imbrication on all quadrants in pig eyes.

    Osamu Sawada, Shumpei Obata, Masashi Kakinoki… in Japanese Journal of Ophthalmology (2022)

  3. No Access

    Article

    Prediction of postoperative visual acuity after vitrectomy for macular hole using deep learning–based artificial intelligence

    To create a model for prediction of postoperative visual acuity (VA) after vitrectomy for macular hole (MH) treatment using preoperative optical coherence tomography (OCT) images, using deep learning (DL)–base...

    Shumpei Obata, Yusuke Ichiyama… in Graefe's Archive for Clinical and Experime… (2022)

  4. Article

    Open Access

    Bex1 is essential for ciliogenesis and harbours biomolecular condensate-forming capacity

    Primary cilia are sensory organelles crucial for organ development. The pivotal structure of the primary cilia is a microtubule that is generated via tubulin polymerization reaction that occurs in the basal bo...

    Emi Hibino, Yusuke Ichiyama, Atsushi Tsukamura, Yosuke Senju, Takao Morimune… in BMC Biology (2022)

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  5. Article

    Open Access

    Endothelial RhoA GTPase is essential for in vitro endothelial functions but dispensable for physiological in vivo angiogenesis

    Imbalanced angiogenesis is a characteristic of several diseases. Rho GTPases regulate multiple cellular processes, such as cytoskeletal rearrangement, cell movement, microtubule dynamics, signal transduction a...

    Fatema Tuz Zahra, Md Sanaullah Sajib, Yusuke Ichiyama… in Scientific Reports (2019)

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  6. No Access

    Chapter

    Vitreomacular Traction Syndrome

    Posterior vitreous detachment (PVD) is commonly seen in the aging eye [1]. Although the majority of PVDs occur without complication, a small proportion can be associated with excessive traction on the macula, ...

    Yusuke Ichiyama, Masahito Ohji in Surgical Retina (2019)

  7. No Access

    Article

    Comparison between wide-angle OCT angiography and ultra-wide field fluorescein angiography for detecting non-perfusion areas and retinal neovascularization in eyes with diabetic retinopathy

    To compare the ability of wide-angle optical coherence tomography angiography (OCTA) with that of ultra-wide field fluorescein angiography (UWFFA) to detect non-perfusion areas (NPAs) or retinal neovasculariza...

    Osamu Sawada, Yusuke Ichiyama, Syunpei Obata… in Graefe's Archive for Clinical and Experime… (2018)

  8. No Access

    Article

    The effectiveness of vitrectomy for diffuse diabetic macular edema may depend on its preoperative optical coherence tomography pattern

    To investigate the effectiveness of vitrectomy for diffuse diabetic macular edema (DDME) and its dependence on optical coherence tomography (OCT) findings.

    Yusuke Ichiyama, Osamu Sawada, Takamasa Mori… in Graefe's Archive for Clinical and Experime… (2016)

  9. Article

    The possible mechanisms of subretinal fluid resolution after vitrectomy

    Yusuke Ichiyama, Masahito Ohji in Graefe's Archive for Clinical and Experime… (2016)

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