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Article
Open AccessWhole-genome resequencing of tea grey geometrid provides insights into their population structure and adaptation to tea crops
Tea grey geometrid, Ectropis grisescens (Lepidoptera: Geometridae), is a chewing defoliator of high fecundity and gluttony, whose larvae heavily consume leaves and shoots, and consequently cause significant losse...
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Article
Open AccessLong non-coding RNA SNHG4 aggravates cigarette smoke-induced COPD by regulating miR-144-3p/EZH2 axis
The purpose of this study was to explore the expression level of SNHG4 in patients with COPD and its diagnostic value in COPD, to probe the biological function of SNHG4 in COPD at the cellular level, and to re...
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Article
Open AccessEffect of multidisciplinary team (MDT) centred on pregnant women with pulmonary hypertension on treatment and outcomes of pregnancy
The importance of multidisciplinary team (MDT) centred on pregnant women with pulmonary hypertension (PH) has been highlighted. However, rare studies have explored its effects on pregnancy outcomes. This study...
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Article
Open AccessA network business availability modeling method based on Markov chain
Military tactical networks (MTNs) have grown in size and complexity as the volume of battlefield communications business has increased dramatically. There is a critical need for a quantitative evaluation metho...
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Article
Open AccessApolipoprotein A5 ameliorates MCT induced pulmonary hypertension by inhibiting ER stress in a GRP78 dependent mechanism
Pulmonary arterial hypertension (PAH) is a chronic, progressive lung vascular disease accompanied by elevated pulmonary vascular pressure and resistance, and it is characterized by increased pulmonary artery s...
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Article
Climate changes in the Lhasa River basin, Tibetan Plateau: irrigation-induced cooling along with a warming trend
Characterizing the response of temperature variables to agricultural irrigation is expected to be an important challenge for understanding the full impact of water management on regional climate change. In thi...
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Article
Hybrids of oxoisoaporphine–tetrahydroisoquinoline: novel multi-target inhibitors of inflammation and amyloid-β aggregation in Alzheimer’s disease
A series of 8- and 11-substituted hybrids of oxoisoaporphine–tetrahydroisoquinoline have been designed and synthesized. The new derivatives strongly suppressed NO and iNOS production and modulated the producti...
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Article
Open AccessSolar water splitting by photovoltaic-electrolysis with a solar-to-hydrogen efficiency over 30%
Hydrogen production via electrochemical water splitting is a promising approach for storing solar energy. For this technology to be economically competitive, it is critical to develop water splitting systems w...
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Article
Open AccessmiR-23a/b regulates the balance between osteoblast and adipocyte differentiation in bone marrow mesenchymal stem cells
Age-related osteoporosis is associated with the reduced capacity of bone marrow mesenchymal stem cells (BMSCs) to differentiate into osteoblasts instead of adipocytes. However, the molecular mechanisms that de...
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Article
Open AccessRelationship of serum GDF11 levels with bone mineral density and bone turnover markers in postmenopausal Chinese women
Growth differentiation factor 11 (GDF11) is an important circulating factor that regulates aging. However, the role of GDF11 in bone metabolism remains unclear. The present study was undertaken to investigate ...
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Article
Open AccessOn-chip plasmonic waveguide optical waveplate
Polarization manipulation is essential in almost every photonic system ranging from telecommunications to bio-sensing to quantum information. This is traditionally achieved using bulk waveplates. With the deve...
