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Article
Open AccessEstimating the spatial correlation and convergence of China's healthcare resources allocation: evidence from the Yangtze River Delta Region
China’s imbalanced allocation of healthcare resources mainly arises from urban–rural and intercity differences, the solution of which has been the goal of reforms during the past decades. Estimating the spatia...
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Article
Open AccessHigh expression of RIPK2 is associated with Taxol resistance in serous ovarian cancer
Taxol resistance in serous ovarian cancer is responsible for its poor prognosis, yet the underlying mechanism is still poorly understood. Thus, we probed the mechanism of Taxol resistance in serous ovarian can...
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Article
Open AccessDevelopment of an immunogenomic landscape for the competing endogenous RNAs network of peri-implantitis
Peri-implantitis is an inflammation that occurs around the implant, resulting in varying degrees of inflammatory damage to the soft and hard tissues. The characteristic criterion is the loss of the supporting ...
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Article
MHC Class I Molecules and PirB Shape Neuronal Morphology by Affecting the Dendritic Arborization of Cortical Neurons
Neuronal MHC class I proteins have been previously reported to regulate synaptic plasticity. Several reports indicate MHC class I proteins are expressed early during development of the nervous system, suggesti...
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Article
Open AccessCan anterior repositioning splint effectively treat temporomandibular joint disc displacement?
The aim of this study was to determine whether anterior repositioning splint (ARS) can effectively treat temporomandibular joint (TMJ) anterior disc displacement with reduction (DDwR) in juvenile Class II pati...
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Article
Ultrafine copper decorated polypyrrole nanotube electrode for nitrite detection
In this report, a nitrite electrochemical sensor was developed by electrochemical deposition of copper nanoparticles on the polypyrrole nanotubes (PPy-Cu). The PPy nanotubes were synthesized via pyrrole polyme...
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Article
Open AccessMYCN drives glutaminolysis in neuroblastoma and confers sensitivity to an ROS augmenting agent
Heightened aerobic glycolysis and glutaminolysis are characteristic metabolic phenotypes in cancer cells. Neuroblastoma (NBL), a devastating pediatric cancer, is featured by frequent genomic amplification of M...
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Article
Open AccessProduction and application of polyclonal and monoclonal antibodies against Spiroplasma eriocheiris
A new species of spiroplasma, Spiroplasma eriocheiris (S. eriocheiris), was identified as a lethal pathogen of tremor disease (TD) in Chinese mitten crab recently. In order to acquire appropriate biological and d...
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Article
Developmental expression and localization of MHC class I molecules in the human central nervous system
Recent animal studies have found neuronal expression of major histocompatibility complex (MHC) class I in the central nervous system (CNS). However, the developmental expression profiles of MHC class I in huma...
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Article
Spatial–Temporal Expression of Non-classical MHC Class I Molecules in the C57 Mouse Brain
Recent studies clearly demonstrate major histocompatibility complex (MHC) class I expression in the brain plays an important functional role in neural development and plasticity. A previous study from our lab...
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Article
Open AccessEnhanced antitumor effects of the BRBP1 compound peptide BRBP1-TAT-KLA on human brain metastatic breast cancer
Novel molecularly targeted agents that block the development and metastasis of human brain metastatic breast cancer hold great promise for their translational value. In this study, we constructed a novel targe...
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Article
The Similar Expression Pattern of MHC Class I Molecules in Human and Mouse Cerebellar Cortex
The major histocompatibility complex (MHC) class I molecules are considered to be important in the immune system. However, the results reported in the past decade indicate that they also play important roles i...
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Article
The Expression Patterns of MHC Class I Molecules in the Developmental Human Visual System
It has been considered that healthy neurons in central nervous system (CNS) do not express major histocompatibility complex (MHC) class I molecules. However, recent studies clearly demonstrated the expression ...
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Article
The Expression Pattern of Classical MHC Class I Molecules in the Development of Mouse Central Nervous System
Classical major histocompatibility complex (MHC) class I, first identified in the immune system, is also expressed in the develo** and adult central nervous system (CNS). Although the MHC class I molecules h...
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Chapter and Conference Paper
Androgen Receptor Mutations Associated with Androgen Insensitivity Syndrome: A High Content Analysis Approach Leading to Personalized Medicine
Androgen insensitivity syndrome (AIS) is a rare disease associated with inactivating mutations of AR that disrupt male sexual differentiation and cause a spectrum of phenotypic abnormalities having as a common...
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Article
A novel one-step strategy for the preparation of HLA/HBc18–27 and HLA/CEA694–702 complexes with ion exchange chromatography
The heavy chain protein of HLA-peptide complexes (HLA/HBc18–27 and HLA/CEA694–702) immobilized onto an ion exchange chromatography column and then the dilution-refolded HBc18–27-fused or CEA694–702-fused β2m prot...
