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  1. No Access

    Article

    H4S47 O-GlcNAcylation regulates the activation of mammalian replication origins

    The transmission and maintenance of genetic information in eukaryotic cells relies on the faithful duplication of the entire genome. In each round of division, excessive replication origins are licensed, with ...

    Yingying Zou, Jiayao Pei, Haizhen Long, Liting Lan… in Nature Structural & Molecular Biology (2023)

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    Article

    Regulation of Tumor Suppressor Gene CDKN2A and Encoded p16-INK4a Protein by Covalent Modifications

    CDKN2A is one of the most studied tumor suppressor genes. It encodes the p16-INK4a protein that plays a critical role in the cell cycle progression, differentiation, senescence, and apoptosis. Mutations in CDKN2A

    Yang Jiao, Yunpeng Feng, **uli Wang in Biochemistry (Moscow) (2018)

  3. No Access

    Article

    Lewis-antigen-containing ICAM-2/3 on Jurkat leukemia cells interact with DC-SIGN to regulate DC functions

    Dendritic cell-specific intercellular adhesion molecule-3-grabbing nonintegrin (DC-SIGN) is an important C-type lectin and plays a critical role in the recognition of pathogens and self-antigens. It has recent...

    **n **, Qingpan Bu, Yingying Zou, Yunpeng Feng, Min Wei in Glycoconjugate Journal (2018)

  4. No Access

    Article

    The proximal GC-rich region of p16INK4a gene promoter plays a role in its transcriptional regulation

    p16INK4a plays a key role in control of cell cycle progression by negatively regulating the CDK4/6 activity. This study establishes that the p16INK4a minimal promoter region required for the transcription factor ...

    **uli Wang, Yunpeng Feng, Lina Pan, Yanle Wang… in Molecular and Cellular Biochemistry (2007)