Health Informatics Data Analysis
Methods and Examples
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Article
A generalized integrated framework for urban public transport operations evaluation based on interval neutrosophic TODIM and EDAS technique
With the acceleration of urbanization construction, the contradiction between supply and demand of urban public transportation resources is becoming increasingly prominent, resulting in increasingly serious pr...
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Chapter and Conference Paper
gaBERT: An Interpretable Pretrained Deep Learning Framework for Cancer Gene Marker Discovery
Cancer classification based on gene expression profiles and the identification of significant oncogenes have become hot research topics in the field of bioinformatics. However, the complexity, high-dimensional...
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Chapter and Conference Paper
RFIR: A Lightweight Network for Retinal Fundus Image Restoration
Retinal fundus images can be utilized for the diagnosis and screening of ocular or other diseases. However, not all devices and operators can directly obtain high-quality retinal images. Low resolution or poor...
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Article
Resonance analysis between deck and cables in cable-stayed bridges with coupling effect of adjacent cables considered
The nonlinear dynamic model of a shallow arch with multiple cables is developed to model a long-span cable-stayed bridge. Based on the veering phenomenon of cable-stayed bridges, the in-plane modal internal re...
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Chapter and Conference Paper
Consistency Formation Maneuver Control Based on Nonlinear Dynamic Inverse
In the process of formation control, the conventional consistent formation control methods often adjust the relative position of each aircraft relative to the formation virtual center node to achieve formation...
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Chapter and Conference Paper
M-US-EMRs: A Multi-modal Data Fusion Method of Ultrasonic Images and Electronic Medical Records Used for Screening of Coronary Heart Disease
Coronary heart disease (CHD) is the leading cause of death and disease burden in China and world-wide. The accurate screening for CHD can be of great value to guiding and facilitating the treatment. Traditiona...
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Chapter and Conference Paper
Multi-BERT-wwm Model Based on Probabilistic Graph Strategy for Relation Extraction
As the core work of information extraction, relation extraction aims to find medical entity pairs with relations from the medical records. The current methods of relation extraction either ignore the relevance...
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Article
A novel hybrid network of fusing rhythmic and morphological features for atrial fibrillation detection on mobile ECG signals
Atrial fibrillation (AF) is one of the most common arrhythmia diseases, the incidence of which is ascendant with age increase. What’s more, AF is a high-risk factor for stroke, ischemia myocardial and other ma...
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Protocol
Albumin-Binding Fatty Acid–Modified Gapmer Antisense Oligonucleotides for Modulation of Pharmacokinetics
Prolonged circulation and modulation of the pharmacokinetic profile are important to improve the clinical potential of antisense oligonucleotides (ASOs). Gapmer ASOs demonstrate excellent nuclease stability an...
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Article
Open AccessA benchmark study of sequence alignment methods for protein clustering
Protein sequence alignment analyses have become a crucial step for many bioinformatics studies during the past decades. Multiple sequence alignment (MSA) and pair-wise sequence alignment (PSA) are two major ap...
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Article
Open AccessAuthor Correction: Multi-label Learning for Predicting the Activities of Antimicrobial Peptides
A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper.
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Article
Open AccessMobile GPU-based implementation of automatic analysis method for long-term ECG
Long-term electrocardiogram (ECG) is one of the important diagnostic assistant approaches in capturing intermittent cardiac arrhythmias. Combination of miniaturized wearable holters and healthcare platforms en...
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Chapter and Conference Paper
Automatic Text Classification for Label Imputation of Medical Diagnosis Notes Based on Random Forest
Electronic medical records (EMRs) contain many information of patients, which are of great value for data mining for various clinical applications. However, information missing, including label missing, is per...
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Article
Rectified-Linear-Unit-Based Deep Learning for Biomedical Multi-label Data
Disease diagnosis is one of the major data mining questions by the clinicians. The current diagnosis models usually have a strong assumption that one patient has only one disease, i.e. a single-label data mining ...
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Article
Open AccessMulti-label Learning for Predicting the Activities of Antimicrobial Peptides
Antimicrobial peptides (AMPs) are peptide antibiotics with a broad spectrum of antimicrobial activities. Activity prediction of AMPs from their amino acid sequences is of great therapeutic importance but impos...
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Book
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Chapter and Conference Paper
Analyses of the Dual Immune Roles Cytokines Play in Ischemic Stroke
Stroke is one of the leading causes of morbidity and permanent disability worldwide. There is a need for an efficacious alternative therapy administered beyond the limitation of time window based on the biolog...
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Chapter
Metagenomics for Monitoring Environmental Biodiversity: Challenges, Progress, and Opportunities
Metagenomics, as the genomic analysis of DNA materials from environmental samples containing multiple genomic components, is attracting more and more interests due to its wide applications on microbial, cancer...
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Article
Open AccessCRISPRdigger: detecting CRISPRs with better direct repeat annotations
Clustered regularly interspaced short palindromic repeats (CRISPRs) are important genetic elements in many bacterial and archaeal genomes, and play a key role in prokaryote immune systems’ fight against invasi...
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Article
Open AccessObtaining Human Ischemic Stroke Gene Expression Biomarkers from Animal Models: A Cross-species Validation Study
Recent studies have revealed the systematic altering of gene expression in human peripheral blood during the early stages of ischemic stroke, which suggests a new potential approach for the rapid diagnosis or ...
