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  1. Article

    Open Access

    Strategic disruption of cancer’s powerhouse: precise nanomedicine targeting of mitochondrial metabolism

    Mitochondria occupy a central role in the biology of most eukaryotic cells, functioning as the hub of oxidative metabolism where sugars, fats, and amino acids are ultimately oxidized to release energy. This cr...

    Pei Lin, Ye Lu, Jiarong Zheng, Yunfan Lin, **nyuan Zhao… in Journal of Nanobiotechnology (2024)

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  2. Article

    Open Access

    Modulating extracellular matrix stiffness: a strategic approach to boost cancer immunotherapy

    The interplay between extracellular matrix (ECM) stiffness and the tumor microenvironment is increasingly recognized as a critical factor in cancer progression and the efficacy of immunotherapy. This review co...

    Zizhao Mai, Yunfan Lin, Pei Lin, **nyuan Zhao, Li Cui in Cell Death & Disease (2024)

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  3. Article

    Open Access

    New frontiers in salivary extracellular vesicles: transforming diagnostics, monitoring, and therapeutics in oral and systemic diseases

    Salivary extracellular vesicles (EVs) have emerged as key tools for non-invasive diagnostics, playing a crucial role in the early detection and monitoring of diseases. These EVs surpass whole saliva in biomark...

    Li Cui, Jiarong Zheng, Ye Lu, Pei Lin, Yunfan Lin… in Journal of Nanobiotechnology (2024)

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  4. No Access

    Chapter and Conference Paper

    Analysis of Fault Mode of Variable Geometry Component on Variable Cycle Engine

    Variable cycle engines achieve superior performance in the all-envelope range by adjusting variable geometry components. The addition of variable geometry components reduces the reliability of engine and makes...

    Yunfan Lin, Hailong Tang, Min Chen… in 2023 Asia-Pacific International Symposium … (2024)

  5. No Access

    Article

    Epitranscriptomic modifications in mesenchymal stem cell differentiation: advances, mechanistic insights, and beyond

    RNA modifications, known as the “epitranscriptome”, represent a key layer of regulation that influences a wide array of biological processes in mesenchymal stem cells (MSCs). These modifications, catalyzed by ...

    Jiarong Zheng, Ye Lu, Yunfan Lin, Shanshan Si, Bing Guo… in Cell Death & Differentiation (2024)