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Chapter and Conference Paper
Renewable Energy System Optimization Decision Method Considering Wind Power Prediction
China’s electricity sector is experiencing a revolutionary transformation, with renewable energy progressively substituting traditional fossil fuels. The emergence of wind power as a major renewable energy sou...
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Article
Open AccessTargeted delivery of a PD-1-blocking scFv by CD133-specific CAR-T cells using nonviral Slee** Beauty transposition shows enhanced antitumour efficacy for advanced hepatocellular carcinoma
CD133 is considered a marker for cancer stem cells (CSCs) in several types of tumours, including hepatocellular carcinoma (HCC). Chimeric antigen receptor-specific T (CAR-T) cells targeting CD133-positive CSCs...
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Article
Open AccessSmartphone-based platforms implementing microfluidic detection with image-based artificial intelligence
The frequent outbreak of global infectious diseases has prompted the development of rapid and effective diagnostic tools for the early screening of potential patients in point-of-care testing scenarios. With a...
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Article
Open AccessCMTM6 inhibits tumor growth and reverses chemoresistance by preventing ubiquitination of p21 in hepatocellular carcinoma
Hepatocellular carcinoma is one of the most common malignancies and has a poor prognosis. The ubiquitin-proteasome pathway is required for the degradation of most short-lived proteins. CMTM6 has been implicate...
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Article
Cancer-cell stiffening via cholesterol depletion enhances adoptive T-cell immunotherapy
Malignant transformation and tumour progression are associated with cancer-cell softening. Yet how the biomechanics of cancer cells affects T-cell-mediated cytotoxicity and thus the outcomes of adoptive T-cell...
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Article
Open AccessInhibition of DTYMK significantly restrains the growth of HCC and increases sensitivity to oxaliplatin
Most patients with hepatocellular carcinoma (HCC) are in the middle or advanced stage at the time of diagnosis, and the therapeutic effect is limited. Therefore, this study aimed to verify whether deoxythymidy...
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Article
Open AccessTargeting Hypoxic Tumors with Hybrid Nanobullets for Oxygen-Independent Synergistic Photothermal and Thermodynamic Therapy
An all-organic hybrid nanobullets labeled as ZPA@HA-ACVA-AZ NBs was developed for the “precise strike”of hypoxic tumors through an oxygen-independently syn...
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Article
Open AccessGalectin-3 favours tumour metastasis via the activation of β-catenin signalling in hepatocellular carcinoma
High probability of metastasis limited the long-term survival of patients with hepatocellular carcinoma (HCC). Our previous study revealed that Galectin-3 was closely associated with poor prognosis in HCC pati...
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Article
Association of ABCB1 C3435T Polymorphism with Echocardiographic Index Among Patients with Atherosclerotic Ischemic Stroke and Transient Ischemic Attack
Emerging evidence has suggested that patients with ischemic stroke (IS) and/or transient ischemic attack (TIA) are more likely to exhibit myocardial disorders, which can be reflected by transthoracic echocardi...
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Article
New 3D potential energy surface and infrared spectrum of Ar—N2O complex in the N2O v3 fundamental vibration region
The goal of this paper was to re-evaluate 3D potential energy surface of the Ar–N2O complex containing N2O monomer v3 stretching vibrations. Two vibrational potentials for v3 = 0, 1 were obtained and then used to...
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Chapter and Conference Paper
A Relay Protocol in AF Relaying Wireless Energy Harvesting Network
In this article, we consider the energy harvesting system of wireless sensor networks with amplify and forward (AF) relay nodes. In this model, the working mode of the relay node is divided into two parts: fir...
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Chapter and Conference Paper
Mobile Sink Data Collection Mechanism for Throughput Maximization with RF Energy Harvesting in WSNs
Recent years have witnessed the studies of mobile vehicle scheduling to recharge sensor nodes via wireless energy transfer technologies. However, most of them just overlook radio frequency (RF) energy harvesti...
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Article
Open AccessClonal evolution in patients with chronic lymphocytic leukaemia develo** resistance to BTK inhibition
Resistance to the Bruton’s tyrosine kinase (BTK) inhibitor ibrutinib has been attributed solely to mutations in BTK and related pathway molecules. Using whole-exome and deep-targeted sequencing, we dissect evolut...
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Article
Low-temperature post-deposition annealing investigation for 3D charge trap flash memory by Kelvin probe force microscopy
The influence of post-deposition annealing (PDA) temperature condition on charge distribution behavior of HfO2 thin films was systematically investigated by various-temperature Kelvin probe force microscopy techn...
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Article
Advances in Experimental Approaches for Investigating Cell Aggregate Mechanics
Cells tend to form hierarchy structures in native tissues. Formation of cell aggregates in vitro such as cancer spheroids and embryonic bodies provides a unique means to study the mechanical properties and biolog...
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Article
Aberrant constitutive activation of nuclear factor κB in glioblastoma multiforme drives invasive phenotype
Several recent studies have shown that aberrant constitutive activation of nuclear factor kappaB (NF-κB) is present in a variety of cancers including gliomas. NF-κB is known to play important roles in the phys...
