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  1. Article

    Open Access

    Allograft Model of Aortic Arch Segment Grafting to Abdominal Aorta Through End-to-Side Anastomosis in Mice

    The mouse aortic transplantation model is a valuable tool for investigating the mechanisms of atherosclerosis regression, but few laboratories can generate it due to the operation difficulty, especially for th...

    Chiyu Liu, Qi Chen, Mingyuan He, Yulin Liao in Journal of Cardiovascular Translational Re… (2024)

  2. Article

    Open Access

    Delayed PCI is not beneficial for STEMI patients with impaired renal function: a retrospective cohort study

    Preexisting impaired renal function (IRF) and contrast-induced nephropathy (CIN) after percutaneous coronary intervention (PCI) in patients with ST-segment elevation myocardial infarction (STEMI) are important...

    Yi Lao, Kaitong Chen, Li Feng, Yong Yuan, ** Zhang in BMC Cardiovascular Disorders (2023)

  3. Article

    Open Access

    Characteristics and significance of peripheral blood T-cell receptor repertoire features in patients with indeterminate lung nodules

    Huaichao Luo, Ruiling Zu, Ziru Huang in Signal Transduction and Targeted Therapy (2022)

  4. Article

    Open Access

    CRIP1 cooperates with BRCA2 to drive the nuclear enrichment of RAD51 and to facilitate homologous repair upon DNA damage induced by chemotherapy

    Homologous recombination (HR) repair is an important determinant of chemosensitivity. However, the mechanisms underlying HR regulation remain largely unknown. Cysteine-rich intestinal protein 1 (CRIP1) is a me...

    Huiying Sun, Rui Zhou, Yannan Zheng, Zhaowei Wen, Dingling Zhang in Oncogene (2021)

  5. Article

    Open Access

    Differences in the clinical presentation, management, and in-hospital outcomes of acute aortic dissection in patients with and without end-stage renal disease

    Few studies have evaluated the clinical presentation, management, and outcomes of patients with end-stage renal disease (ESRD) presenting with acute aortic dissection (AAD) in real-world clinical practice. Thu...

    Jiahe **e, Shan Zeng, Long **e, Rongming Ding, **g Hu, Hong Zeng in BMC Nephrology (2021)

  6. Article

    Open Access

    The geriatric nutrition risk index versus the mini-nutritional assessment short form in predicting postoperative delirium and hospital length of stay among older non-cardiac surgical patients: a prospective cohort study

    Malnutrition has been shown to be associated with poor prognosis in older surgical patients. Several tools are available for detecting malnutrition. But little is known about their ability to assess risks of p...

    Yanli Zhao, Ning Ge, Dongmei **e, Langli Gao, Yanyan Wang, Yulin Liao in BMC Geriatrics (2020)

  7. Article

    Open Access

    Immune cell infiltration as a biomarker for the diagnosis and prognosis of stage I–III colon cancer

    Tumour-infiltrating immune cells are a source of important prognostic information for patients with resectable colon cancer. We developed a novel immune model based on systematic assessments of the immune land...

    Rui Zhou, **gwen Zhang, Dongqiang Zeng, Huiying Sun in Cancer Immunology, Immunotherapy (2019)

  8. No Access

    Article

    Comparison of Magnetic Microbubbles and Dual-modified Microbubbles Targeted to P-selectin for Imaging of Acute Endothelial Inflammation in the Abdominal Aorta

    Ultrasound molecular imaging (UMI) has potential to evaluate an inflammatory profile of endothelium. However, it is less successful in large arteries. This study compared magnetic microbubbles (MBs) selectivel...

    Weilan Wu, Xuguang Feng, Ye Yuan, Ying Liu, Meiyu Li in Molecular Imaging and Biology (2017)

  9. Article

    Open Access

    Acute hyperglycemia suppresses left ventricular diastolic function and inhibits autophagic flux in mice under prohypertrophic stimulation

    Left ventricular (LV) dysfunction is closely associated with LV hypertrophy or diabetes, as well as insufficient autophagic flux. Acute or chronic hyperglycemia is a prognostic factor for patients with myocard...

    Jiahe **e, Kai Cui, Huixin Hao, Yingxue Zhang, Hairuo Lin in Cardiovascular Diabetology (2016)

  10. Article

    Open Access

    Effects of mineralocorticoid receptor antagonists in patients with preserved ejection fraction: a meta-analysis of randomized clinical trials

    Mineralocorticoid receptor antagonists (MRAs) have been shown to be effective in patients with heart failure or myocardial infarction complicated by a reduced ejection fraction. However, the role of MRAs in pa...

    Yanmei Chen, He Wang, Yongkang Lu, **aobo Huang, Yulin Liao, Jian** Bin in BMC Medicine (2015)

  11. No Access

    Article

    Histamine H2 receptor activation exacerbates myocardial ischemia/reperfusion injury by disturbing mitochondrial and endothelial function

    There is evidence that H2R blockade improves ischemia/reperfusion (I/R) injury, but the underlying cellular mechanisms remain unclear. Histamine is known to increase vascular permeability and induce apoptosis,...

    Tao Luo, Baihe Chen, Zonglei Zhao, Nvqin He, Zhi Zeng in Basic Research in Cardiology (2013)

  12. Article

    Inhibition of Cardiac Remodeling by Pravastatin Is Associated with Amelioration of Endoplasmic Reticulum Stress

    The aim of this study is to investigate whether pravastatin can inhibit cardiac remodeling and ameliorate endoplasmic reticulum (ER) stress caused by pressure overload or tumor necrosis factor α (TNFα). Either pr...

    Hui Zhao, Yulin Liao, Tetsuo Minamino, Yoshihiro Asano in Hypertension Research (2008)

  13. Article

    Atorvastatin Slows the Progression of Cardiac Remodeling in Mice with Pressure Overload and Inhibits Epidermal Growth Factor Receptor Activation

    The aim of this study was to investigate whether atorvastatin inhibits epidermal growth factor receptor (EGFR) activation in cardiomyocytes in vitro and slows the progression of cardiac remodeling induced by pres...

    Yulin Liao, Hui Zhao, Akiko Ogai, Hisakazu Kato, Masanori Asakura in Hypertension Research (2008)

  14. Article

    Impact of Adenosine Receptor Signaling and Metabolism on Pathophysiology in Patients with Chronic Heart Failure

    Adenosine is well known to be a cardioprotective substance in ischemic heart disease. However, the modulation of adenosine receptors and the production and degradation of endogenous adenosine in chronic heart ...

    Masanori Asakura, Hiroshi Asanuma, Jiyoong Kim, Yulin Liao in Hypertension Research (2007)