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    Article

    A new lymphedema treatment using pyro-drive jet injection

    Lymphedema, resulting from impaired lymphatic drainage, causes inflammation, fibrosis and tissue damage leading to symptoms such as limb swelling and restricted mobility. Despite various treatments under explo...

    Megumi Nishiyama, Yuko Sakaguchi, Sayuri Morito, Kei Nagase in Human Cell (2024)

  2. No Access

    Article

    Development of a useful single-reference HPLC method for therapeutic drug monitoring of phenytoin and carbamazepine in human plasma

    A single reference high-performance liquid chromatographic (SR-HPLC) method was developed and validated for the therapeutic drug monitoring (TDM) of phenytoin (PHT) and carbamazepine (CBZ) in plasma from patie...

    Yuko Sakaguchi, Ryo Arima, Runa Maeda, Takuji Obayashi in Analytical Sciences (2023)

  3. Article

    Open Access

    Stable Immune Response Induced by Intradermal DNA Vaccination by a Novel Needleless Pyro-Drive Jet Injector

    DNA vaccination can be applied to the treatment of various infectious diseases and cancers; however, technical difficulties have hindered the development of an effective delivery method. The efficacy of a DNA ...

    Chinyang Chang, Jiao Sun, Hiroki Hayashi, Ayano Suzuki, Yuko Sakaguchi in AAPS PharmSciTech (2019)