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Article
Open AccessTargeting Poly(ADP)ribose polymerase in BCR/ABL1-positive cells
BCR/ABL1 causes dysregulated cell proliferation and is responsible for chronic myelogenous leukemia (CML) and Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph1-ALL). In addition to the deregul...
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Article
Open AccessDevelopment of a prognostic composite cytokine signature based on the correlation with nivolumab clearance: translational PK/PD analysis in patients with renal cell carcinoma
Although several therapeutic options for patients with renal cell carcinoma (RCC) have been approved over recent years, including immune checkpoint inhibitors, considerable need remains for molecular biomarker...
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Article
Conferring virus resistance in tomato by independent RNA silencing of three tomato homologs of Arabidopsis TOM1
The TOM1/TOM3 genes from Arabidopsis are involved in the replication of tobamoviruses. Tomato homologs of these genes, LeTH1, LeTH2 and LeTH3, are known. In this study, we examined transgenic tomato lines where i...
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Protocol
PMO Delivery System Using Bubble Liposomes and Ultrasound Exposure for Duchenne Muscular Dystrophy Treatment
Duchenne muscular dystrophy (DMD) is a genetic disorder characterized by progressive muscle degeneration, caused by nonsense or frameshift mutations in the dystrophin (DMD) gene. Antisense oligonucleotides can...
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Article
Acceleration time ratio for the assessment of extracranial internal carotid artery stenosis
To apply the acceleration time (AcT) ratio as an additional marker for diagnosing internal carotid artery (ICA) stenosis.
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Article
Microbial biodegradation of a novel fluorotelomer alcohol, 1H,1H,2H,2H,8H,8H-perfluorododecanol, yields short fluorinated acids
The accumulation of perfluorooctanoic acid (PFOA) has been detected in wildlife, soil, and water. Further, 8:2 fluorotelomer alcohol (8:2 FTOH) is used for the industrial synthesis of other fluorotelomer compo...
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Article
Influence of cosmetically tinted soft contact lenses on higher-order wavefront aberrations and visual performance
To investigate the influence of cosmetically tinted soft contact lenses on ocular higher-order aberrations and visual performance, and to analyze the relationship between these parameters after the lens wear.
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Article
Sustained complete cytogenetic remission in a patient with chronic myeloid leukemia after discontinuation of imatinib mesylate therapy
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Article
Hypereosinophilia in a Patient with Invasive Thymoma with Clonal T-Lymphocyte Expansion Expressing CD4, CD8, and CD25 Antigens
We report the case of a patient with hypereosinophilia and invasive thymoma harboring probable clonal proliferation of CD4+, CD8+, and CD25+ T-lymphocytes. A 64-year-old woman had eosinophilia (14.1 × 109/L) and ...
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Article
Effect of Surfactants on Atomic Absorption Spectrometry for the Determination of Calcium in the Presence of Phosphate
The atomic absorption of calcium with air-acetylene flame is interfered with by the presence of phosphate. It was found that the interference was reduced by adding Triton X-100 into the calcium solution. The a...
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Article
Co-precipitation of Calcium Carbonate and Barium Carbonate at High Temperature
Ammonium carbonate solution was added into a solution of calcium and barium maintained at 90°C, and a carbonate precipitate was produced. Co-precipitation of calcium carbonate and barium carbonate was investig...