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  1. Article

    Open Access

    Determining prognostic indicator for anticoagulant therapy in sepsis-induced disseminated intravascular coagulation

    There is no reliable indicator that can assess the treatment effect of anticoagulant therapy for sepsis-associated disseminated intravascular coagulation (DIC) in the short term. The aim of this study is to de...

    Toshiaki Iba, Kazuma Yamakawa, Yuki Shiko, Ryo Hisamune in Journal of Intensive Care (2024)

  2. Article

    Open Access

    Assessment of pre-extubating recurrent laryngeal nerve palsy using ultrasound in postoperative patients with esophageal cancer: a prospective observational study

    Ultrasound performed after extubation has been suggested to be useful for the diagnosis of recurrent laryngeal nerve (RLN) paralysis. However, the use of ultrasound for this purpose before extubation has not b...

    Tomomi Kaneko, Takao Kato, Yuki Shiko, Yohei Kawasaki in Journal of Anesthesia (2024)

  3. No Access

    Article

    Comparison of the effect of surgical versus transcatheter aortic valve replacement on the development of postoperative acute kidney injury

    Acute kidney injury (AKI) frequently occurs after cardiac surgery. Recently, transcatheter aortic valve implantation (TAVI), a less invasive option for aortic stenosis (AS), has been increasingly performed, pa...

    Takaomi Nomi, Akira Kitamura, Miki Tsujita, Yuki Shiko, Yohei Kawasaki in Heart and Vessels (2024)

  4. No Access

    Article

    Volume–outcome relationships for extracorporeal membrane oxygenation in acute myocardial infarction

    Acute myocardial infarction (MI) is one of the major scenarios of extracorporeal membrane oxygenation (ECMO) use. The utilization of mechanical circulatory support systems including ECMO varies widely at the h...

    Yuichi Saito, Kazuya Tateishi, Masato Kanda in Cardiovascular Intervention and Therapeuti… (2024)

  5. Article

    Open Access

    Urine collection using a 3-way urethral catheter for PuO2

    Takao Kato, Yuki Shiko, Kaoru Koyama in Journal of Anesthesia (2024)

  6. Article

    Open Access

    Protocolized oxytocin infusion for elective cesarean delivery: a retrospective before-and-after study

    To elucidate the clinical impact of the novel oxytocin protocol using a syringe pump with a stratified dose compared with the conventional practice of putting oxytocin into the bag.

    Azusa Nagai, Yuki Shiko, Shohei Noguchi, Yusuke Ikeda in Journal of Anesthesia (2024)

  7. No Access

    Article

    The effect of assisted reproductive technology on postpartum bleeding: hormonal cycle frozen embryo transfer might increase blood loss

    Among assisted reproductive technologies, frozen thawed embryo transfer (FET) is associated with increased blood loss at delivery. Anesthesiologists need to be aware of new factors that affect postpartum blood...

    Mizuki Taniguchi, Chieko Akinaga, Kota Suzuki, Kaori Tarui in Journal of Anesthesia (2024)

  8. Article

    Open Access

    Risk factors of unintentional piecemeal resection in endoscopic mucosal resection for colorectal polyps ≥ 10 mm

    This study aimed to investigate the lesion and endoscopist factors associated with unintentional endoscopic piecemeal mucosal resection (uniEPMR) of colorectal lesions ≥ 10 mm. uniEPMR was defined from the med...

    Tsubasa Ishikawa, Kenichiro Okimoto, Tomoaki Matsumura in Scientific Reports (2024)

  9. Article

    Open Access

    Efficacy and safety of transdermal electrical stimulation in patients with nonarteritic anterior ischemic optic neuropathy

    No effective treatment for NAION with strong evidence has been established till date. The aim of this investigator-led, prospective, non-randomized, open-label, uncontrolled multi-center exploratory clinical t...

    Gen Miura, Tadami Fujiwara, Yoshihito Ozawa, Yuki Shiko in Bioelectronic Medicine (2023)

  10. Article

    Open Access

    Combined effect of DBM, PRP, and bone marrow fluid on bone union in a rat posterolateral fusion model

    Platelet-rich plasma (PRP) promotes bone union through osteoinduction. We investigated whether adding demineralized bone matrix (DBM), derived naturally from biomaterial and with various growth factors, for os...

    Takuma Otagiri, Yasuhiro Shiga, Takashi Hozumi, Yusuke Matsuura in Scientific Reports (2023)

  11. Article

    Open Access

    Clinical outcomes of surgical treatment for end-stage ankle osteoarthritis in patients aged ≥ 75 years: a multicenter, retrospective study

    This study aimed to clarify the clinical outcomes of surgical treatment for end-stage ankle osteoarthritis in patients aged ≥ 75 years and compare these outcomes with those of patients aged < 75 years.

    Kentaro Amaha, Satoshi Yamaguchi in Journal of Orthopaedic Surgery and Research (2023)

  12. No Access

    Article

    Characteristics and comparative study of thoracolumbar spine injury and dislocation fracture due to tertiary trauma

    Thoracolumbar spine injury is frequently seen with high-energy trauma but dislocation fractures are relatively rare in spinal trauma, which is often neurologically severe and requires urgent treatment. Therefo...

    Hiromitsu Takaoka, Yawara Eguchi, Keita Shibahashi, Ei Ozone in European Spine Journal (2023)

  13. No Access

    Article

    Oral antibiotics and a low-residue diet reduce the incidence of anastomotic leakage after left-sided colorectal surgery: a retrospective cohort study

    Anastomotic leakage is a potential complication after colorectal surgery. We investigated the effects of oral antibiotics and a low-residue diet on the incidence of anastomotic leakage after left-sided colorec...

    Takafumi Nakazawa, Masashi Uchida, Takaaki Suzuki in Langenbeck's Archives of Surgery (2022)

  14. Article

    Open Access

    Mixed venous oxygen tension is a crucial prognostic factor in pulmonary hypertension: a retrospective cohort study

    The prognostic value of mixed venous oxygen tension (PvO2) at pulmonary hypertension diagnosis treated with selective pulmonary vasodilators remains unclear. This study sought to investigate the association of Pv...

    Jun Nagata, Ayumi Sekine, Nobuhiro Tanabe, Yu Taniguchi in BMC Pulmonary Medicine (2022)

  15. Article

    Open Access

    Randomized clinical trial comparing intravitreal aflibercept combined with subthreshold laser to intravitreal aflibercept monotherapy for diabetic macular edema

    To compare the efficacy and safety of intravitreal aflibercept with three loading doses + pro re nata regimen combined with subthreshold laser application to that of IVA monotherapy on eyes with diabetic macul...

    Tomoaki Tatsumi, Yoko Takatsuna, Toshiyuki Oshitari, Tomomi Kaiho in Scientific Reports (2022)

  16. Article

    Open Access

    Automated detection of anterior cruciate ligament tears using a deep convolutional neural network

    The development of computer-assisted technologies to diagnose anterior cruciate ligament (ACL) injury by analyzing knee magnetic resonance images (MRI) would be beneficial, and convolutional neural network (CN...

    Yusuke Minamoto, Ryuichiro Akagi, Satoshi Maki, Yuki Shiko in BMC Musculoskeletal Disorders (2022)

  17. Article

    Open Access

    Intra-articular injection of monoiodoacetate induces diverse hip osteoarthritis in rats, depending on its dose

    Monoiodoacetate (MIA)-induced arthritis models are used widely in osteoarthritis (OA) research to develop effective conservative treatments for hip OA, as an alternative to joint replacement surgery. In joint ...

    Satoshi Yoh, Yuya Kawarai, Shigeo Hagiwara, Sumihisa Orita in BMC Musculoskeletal Disorders (2022)

  18. No Access

    Article

    A 2-year longitudinal study of skeletal muscle mass in women over 40 years of age with degenerative lumbar scoliosis

    We investigated changes in skeletal muscle mass and bone mineral density in degenerative lumbar scoliosis (DLS) patients during a 2-year follow-up following diagnosis.

    Masaya Mizutani, Yawara Eguchi, Toru Toyoguchi, Sumihisa Orita in European Spine Journal (2022)

  19. Article

    Open Access

    Lowering the setting value of the esophageal endoscopic submucosal dissection device enabled tissue damage control in vitro porcine model

    One of the complications of esophageal endoscopic submucosal dissection (ESD) is postoperative stricture formation. Stenosis formation is associated with inflammation and fibrosis in the healing process. We hy...

    Yukiko Yamaguchi, Masaya Uesato, Shohei Yonemoto, Tetsuro Maruyama in Scientific Reports (2022)

  20. Article

    Open Access

    Analysis of the variable factors affecting changes in the blood concentration of cyclosporine before and after transfusion of red blood cell concentrate

    The blood concentration of cyclosporine (CyA) is frequently elevated following the transfusion of red blood cell concentrate (RCC) to patients after allogeneic hematopoietic stem cell transplantation (HSCT). T...

    Masashi Uchida, Natsumi Hanada in Journal of Pharmaceutical Health Care and … (2022)

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