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  1. Article

    Open Access

    Enzymatic activity of a subtilisin homolog, Tk-SP, from Thermococcus kodakarensisin detergents and its ability to degrade the abnormal prion protein

    Tk-SP is a member of subtilisin-like serine proteases from a hyperthermophilic archaeon Thermococcus kodakarensis. It has been known that the hyper-stable protease, Tk-SP, could exhibit enzymatic activity even at...

    Azumi Hirata, Yuki Hori, Yuichi Koga, Jun Okada, Akikazu Sakudo in BMC Biotechnology (2013)