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  1. No Access

    Article

    Improvement of liver histology in hepatic sarcoidosis due to treatment with corticosteroids and ursodeoxycholic acid: a case report

    We report the case of a 48-year-old male with a history of pulmonary and ocular sarcoidosis. Non-caseating granulomas, identified histologically, are the most characteristic manifestation of sarcoidosis. Hepat...

    Mayuko Kikuchi, Aritoshi Koizumi, Tadashi Namisaki in Clinical Journal of Gastroenterology (2024)

  2. Article

    Open Access

    Clinical Benefit of Switching from Low-Dose to High-Dose Empagliflozin in Patients with Type 2 Diabetes

    Sodium-dependent glucose cotransporter 2 (SGLT2) inhibitors ameliorate blood glucose levels in patients with type 2 diabetes mellitus (T2DM) by inhibiting the reabsorption of glucose from the kidneys, thus inc...

    Takeshi Matsumura, Tomoko Makabe, Seiko Ueda, Yuki Fujimoto in Diabetes Therapy (2022)

  3. Article

    Open Access

    Topological confinement of vortices in two-flavor dense QCD

    We find a novel confinement mechanism in the two-flavor dense quark matter proposed recently, that consists of the 2SC condensates and the P-wave diquark condensates of d-quarks. This quark matter exhibiting colo...

    Yuki Fujimoto, Muneto Nitta in Journal of High Energy Physics (2021)

  4. Article

    Open Access

    Extensive studies of the neutron star equation of state from the deep learning inference with the observational data augmentation

    We discuss deep learning inference for the neutron star equation of state (EoS) using the real observational data of the mass and the radius. We make a quantitative comparison between the conventional polynomi...

    Yuki Fujimoto, Kenji Fukushima, Koichi Murase in Journal of High Energy Physics (2021)

  5. Article

    Open Access

    Development of fully automated and ultrasensitive assays for urinary adiponectin and their application as novel biomarkers for diabetic kidney disease

    Glomerular filtration rate (GFR) and urinary albumin excretion rate (UAER) are used to diagnose and classify the severity of chronic kidney disease. Total adiponectin (T-AN) and high molecular weight adiponect...

    Toshihiro Watanabe, Yuki Fujimoto, Aya Morimoto, Mai Nishiyama in Scientific Reports (2020)

  6. No Access

    Chapter and Conference Paper

    A Proposal of Estimating Method for Agreement in Face-to-Face Communication

    Generally, in the meeting exchange of opinions, sharing of knowledge, and creation of new ideas are performed through the discussion. However it is difficult to make sure whether the participants agree with th...

    Masashi Okubo, Yuki Fujimoto in Human Interface and the Management of Info… (2020)

  7. No Access

    Article

    Construction of a 6/5/9-membered tricyclic structure of cladiellins via radical-polar crossover reaction

    A three-component coupling reaction of structurally simple 68 was successfully applied for expeditious synthesis of the 6/5/9-membered tricyclic structure 3 of cladieunicellin D (1) and klysimplexin U (2). Upon ...

    Masanori Nagatomo, Yuki Fujimoto, Keisuke Masuda in The Journal of Antibiotics (2019)

  8. No Access

    Chapter and Conference Paper

    A Neural Network Model with Bidirectional Whitening

    We present here a new model and algorithm which performs an efficient Natural gradient descent for multilayer perceptrons. Natural gradient descent was originally proposed from a point of view of information g...

    Yuki Fujimoto, Toru Ohira in Artificial Intelligence and Soft Computing (2018)

  9. No Access

    Chapter and Conference Paper

    Integration of Sound and Image Data for Detection of Sleep Apnea

    To detect sleep apnea syndrome (SAS), we propose a method that integrates sound and image processing results using overnight sound and video data. In sound processing, snoring sounds are initially extracted us...

    Takehiro Kasahara, Kota Nomura in Proceedings of the Eleventh International … (2018)

  10. Article

    Open Access

    Exogenous gene transfer of Rab38 small GTPase ameliorates aberrant lung surfactant homeostasis in Ruby rats

    Rab38 small GTPase regulates intracellular transport in melanocytes and alveolar type II epithelial cells. Ruby rats carrying Rab38 and other gene mutations exhibit oculocutaneous albinism, bleeding diathesis, an...

    Kazuhiro Osanai, Keisuke Nakase, Takashi Sakuma, Kazuaki Nishiki in Respiratory Research (2017)

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    Article

    Automatic ROI construction for analyzing time–signal intensity curve in dynamic contrast-enhanced MR imaging of the breast

    Our purpose in this study was to construct a 3-dimensional (3D) region of interest (ROI) for analyzing the time–signal intensity curve (TIC) semi-automatically in dynamic contrast-enhanced magnetic resonance (...

    Koya Fujimoto, Yasuyuki Ueda, Shohei Kudomi in Radiological Physics and Technology (2016)