Skip to main content

3 Result(s)

within Yuheng Shan Remove this filter

and

  1. No Access

    Article

    The ATP-Binding Cassette Transporter-Mediated Efflux Transport of Ganciclovir at the Blood–Brain Barrier

    Recent studies have highlighted the key role of the ATP-binding cassette (ABC) transporters, including the P-glycoprotein (P-gp), the breast cancer resistance protein (BCRP), and the multi-drug resistance prot...

    Yuheng Shan, Yuying Cen, **aojiao Xu… in European Journal of Drug Metabolism and Ph… (2024)

  2. No Access

    Article

    Effect of P-glycoprotein Inhibition on the Penetration of Ceftriaxone Across the Blood–Brain Barrier

    Recent studies indicate that inhibition of the efflux transporter P-glycoprotein (P-gp) at the blood–brain barrier (BBB) may represent a putative strategy to increase the BBB penetration of several antibiotics...

    Yuheng Shan, Yuying Cen, Yan** Zhang, Ruishu Tan, Jiahua Zhao… in Neurochemical Research (2022)

  3. No Access

    Article

    Acyclovir Brain Disposition: Interactions with P-gp, Bcrp, Mrp2, and Oat3 at the Blood–Brain Barrier

    Acyclovir is effective in treating herpes simplex virus infections of the central nervous system. The purpose of this study was to investigate the interactions between acyclovir and the efflux pumps P-glycopro...

    Yuheng Shan, Yuying Cen, Yan** Zhang… in European Journal of Drug Metabolism and Ph… (2022)