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  1. Article

    Open Access

    Advancing targeted combination chemotherapy in triple negative breast cancer: nucleolin aptamer-mediated controlled drug release

    Triple-negative breast cancer (TNBC) is a recurrent, heterogeneous, and invasive form of breast cancer. The treatment of TNBC patients with paclitaxel and fluorouracil in a sequential manner has shown promisin...

    Yuan Ma, Duoli **e, Zefeng Chen, … in Journal of Translational Medicine (2024)

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  2. No Access

    Chapter

    Small RNAs in Cancer Therapy

    Gene-based therapy plays a crucial role in precision medicine through gene inhibition, addition, replacement, or editing. This approach has achieved remarkable success in the treatment of many diseases such as...

    Yufei Pan, Quanxin Wang, Yuan Ma (2024)

  3. No Access

    Article

    Intensity-modulated radiotherapy alone compared with intensity-modulated radiotherapy plus concurrent chemotherapy in intermediate-risk nasopharyngeal carcinoma

    This study aimed to investigate the clinical benefit of adding concurrent chemotherapy to intensity-modulated radiotherapy (IMRT) for nasopharyngeal carcinoma (NPC) patients with an intermediate risk (stage II...

    Shufang Liao, Bin Zhang, Yixin Su, Yufei Pan, Jian Zhang… in Strahlentherapie und Onkologie (2024)

  4. Article

    Open Access

    URI alleviates tyrosine kinase inhibitors-induced ferroptosis by reprogramming lipid metabolism in p53 wild-type liver cancers

    The clinical benefit of tyrosine kinase inhibitors (TKIs)-based systemic therapy for advanced hepatocellular carcinoma (HCC) is limited due to drug resistance. Here, we uncover that lipid metabolism reprogramm...

    Zhiwen Ding, Yufei Pan, Taiyu Shang, Tianyi Jiang, Yunkai Lin… in Nature Communications (2023)

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  5. No Access

    Article

    Adversarial domain adaptation for cross-project defect prediction

    Cross-Project Defect Prediction (CPDP) is an attractive topic for locating defects in projects with little labeled data (target projects) by using the prediction model from other projects with sufficient data ...

    Hengjie Song, Guobin Wu, Le Ma, Yufei Pan, Qingan Huang… in Empirical Software Engineering (2023)

  6. Article

    Open Access

    The therapeutic effect of KSP inhibitors in preclinical models of cholangiocarcinoma

    Cholangiocarcinoma (CCA) is an epithelial malignancy with a dismal prognosis owing to limited treatment options. Here, we identified several compound candidates against CCA using a high-throughput drug screen ...

    Yuanyuan Shi, **aowen Cui, Tianyi Jiang, Yufei Pan, Yunkai Lin… in Cell Death & Disease (2022)

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  7. No Access

    Article

    Superiority of intensity-modulated radiation therapy in nasopharyngeal carcinoma with skull-base invasion

    To compare the clinical results and functional outcomes between two-dimensional conventional radiation therapy (2DRT) and intensity-modulated radiation therapy (IMRT) in nasopharyngeal carcinoma (NPC) with sku...

    Shufang Liao, Yuan **e, Yi Feng… in Journal of Cancer Research and Clinical On… (2020)