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Article
Open AccessAuthor Correction: Type-printable photodetector arrays for multichannel meta-infrared imaging
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Article
Open AccessType-printable photodetector arrays for multichannel meta-infrared imaging
Multichannel meta-imaging, inspired by the parallel-processing capability of neuromorphic computing, offers considerable advancements in resolution enhancement and edge discrimination in imaging systems, exten...
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Article
Pan-Cancer Analysis Shows that KIFC2 is a Potential Prognostic and Immunotherapeutic Biomarker for Multiple Cancer Types Including Bladder Cancer
KIFC2 plays an important role in prostate cancer progression and chemotherapy resistance, but the mechanism of its involvement in other malignancies remains unclear. Therefore, this study aimed to analyze and ...
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Article
Open AccessExosomal miR-9-5p derived from iPSC-MSCs ameliorates doxorubicin-induced cardiomyopathy by inhibiting cardiomyocyte senescence
Doxorubicin (DOX) is a chemotherapeutic agent widely used for tumor treatment. Nonetheless its clinical application is heavily limited by its cardiotoxicity. There is accumulated evidence that transplantation ...
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Article
Sema4D as a biomarker for Predicting rheumatoid arthritis disease activity
The semaphorins are membrane or secreted proteins first identified in neural development. Semaphorin 4D (Sema4D) is the first family member found to have immune properties. We evaluated the potential of Sema4D...
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Article
Open AccessMicroRNA-19b-3p dysfunction of mesenchymal stem cell-derived exosomes from patients with abdominal aortic aneurysm impairs therapeutic efficacy
Senescence of vascular smooth muscle cells (VSMCs) contributes to the formation of abdominal aortic aneurysm (AAA). Although mesenchymal stem cell exosomes (MSC-EXO) have been confirmed to restrict the develop...
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Article
Open AccessEmerging steel frames with Fe-SMA U-shaped dampers for enhancing seismic resilience
Post-earthquake financial loss of structures induced by residual inter-story deformation (RID) has been recently noticed and various strategies have been proposed. A newly-emerged energy-dissipation material, ...
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Article
Optimal time point of response assessment for predicting survival is associated with tumor burden in hepatocellular carcinoma receiving repeated transarterial chemoembolization
Objective response rate (ORR) under mRECIST criteria after transarterial chemoembolization (TACE) is a well-perceived surrogate endpoint of overall survival (OS). However, its optimal time point remains contro...
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Article
Open AccessHemin enhances the cardioprotective effects of mesenchymal stem cell-derived exosomes against infarction via amelioration of cardiomyocyte senescence
Application of mesenchymal stem cell-derived exosomes (MSC-EXO) has emerged as a novel therapeutic strategy for myocardial infarction (MI). Our previous study showed that pretreatment with hemin, a potent heme...
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Article
Activation of TIR signalling boosts pattern-triggered immunity
Plant immune responses are mainly activated by two types of receptor. Pattern recognition receptors localized on the plasma membrane perceive extracellular microbial features, and nucleotide-binding leucine-ri...
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Article
Open AccessConditioned medium from induced pluripotent stem cell-derived mesenchymal stem cells accelerates cutaneous wound healing through enhanced angiogenesis
Mesenchymal stem cells (MSCs) can improve cutaneous wound healing via the secretion of growth factors. However, the therapeutic efficacy of MSCs varies depending upon their source. Induced pluripotent stem cel...
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Article
Open AccessMacrophage migration inhibitory factor facilitates the therapeutic efficacy of mesenchymal stem cells derived exosomes in acute myocardial infarction through upregulating miR-133a-3p
Exosome transplantation is a promising cell-free therapeutic approach for the treatment of ischemic heart disease. The purpose of this study was to explore whether exosomes derived from Macrophage migration in...
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Article
Open AccessInhibition of miR-199a-5p rejuvenates aged mesenchymal stem cells derived from patients with idiopathic pulmonary fibrosis and improves their therapeutic efficacy in experimental pulmonary fibrosis
Idiopathic pulmonary fibrosis (IPF) is an age-related disease with no cure. Mesenchymal stem cell (MSC)-based therapy has emerged as a novel strategy for IPF treatment. Nevertheless, MSCs derived from patients...
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Chapter and Conference Paper
Measuring Strain Distribution of Knee Cartilage Using Digital Volume Correlation
The purpose of this study is to measure three-dimensional deformation of the porcine knee joint articular cartilage under compressive load by using digital volume correlation. The compression tester is constru...
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Article
Open AccessAdult mesenchymal stem cell ageing interplays with depressed mitochondrial Ndufs6
Mesenchymal stem cell (MSC)-based therapy has emerged as a novel strategy to treat many degenerative diseases. Accumulating evidence shows that the function of MSCs declines with age, thus limiting their regen...
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Article
A structural view of salicylic acid perception
Salicylic acid (SA) is an essential hormone for plant immune responses. In Arabidopsis, SA is perceived by two groups of receptors, NPR1 and NPR3/4, which play opposite roles in regulating defence gene expression...
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Article
Exosomes: Cell-Free Therapy for Cardiovascular Diseases
Cardiovascular diseases (CVDs) are an important cause of death and disease worldwide. Because injured cardiac tissue cannot be repaired itself, it is urgent to develop other alternate therapies. Stem cells can...
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Article
Open AccessMechanisms underlying the protective effects of mesenchymal stem cell-based therapy
Mesenchymal stem cells (MSCs) have been extensively investigated for the treatment of various diseases. The therapeutic potential of MSCs is attributed to complex cellular and molecular mechanisms of action in...
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Chapter and Conference Paper
Refinement Measurement and Evaluation of Streets in Shanghai Old City
The street is a basic urban linear open space, whose main functions are transportation, municipal administration, landscape and communication. In the past, people focused on streets as an urban space with tran...
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Chapter and Conference Paper
Experimental Evaluation of Pad Degradation of Helmet for American Football and Its Application to Numerical Design
American football is a sport that requires high safety precaution for players because it entails very fast and powerful movements. The players’ helmets are one of the most important means of ensuring their sa...