10 Result(s)

Article

An individualized immune signature of pretreatment biopsies predicts pathological complete response to neoadjuvant chemoradiotherapy and outcomes in patients with esophageal squamous cell carcinoma

No clinically available biomarkers can predict pathological complete response (pCR) for esophageal squamous cell carcinomas (ESCCs) with neoadjuvant chemoradiotherapy (nCRT). Considering that antitumor immunit...

Chaoqi Zhang, Guochao Zhang, Nan Sun… in Signal Transduction and Targeted Therapy (2020)

Article

The landscape of m⁶A regulators in small cell lung cancer: molecular characteristics, immuno-oncology features, and clinical relevance

Chaoqi Zhang, Zhihui Zhang, Zhen Zhang, Yuejun Luo, Peng Wu… in Molecular Cancer (2021)

Article

m⁶A regulators as predictive biomarkers for chemotherapy benefit and potential therapeutic targets for overcoming chemotherapy resistance in small-cell lung cancer

Small-cell lung cancer (SCLC) is a devastating subtype of lung cancer with few therapeutic options. Despite the advent of immunotherapy, platinum-based chemotherapy is still the irreplaceable first-line therap...

Zhihui Zhang, Chaoqi Zhang, Zhaoyang Yang… in Journal of Hematology & Oncology (2021)

Article

An immune-related lncRNA signature predicts prognosis and adjuvant chemotherapeutic response in patients with small-cell lung cancer

Patients with small-cell lung cancer (SCLC) are burdened by limited treatment options and the disease’s dismal prognosis. Long non-coding RNAs (lncRNAs) are essential regulators of genetic alteration and are a...

Zhihui Zhang, Yuejun Luo, Chaoqi Zhang, Peng Wu, Guochao Zhang… in Cancer Cell International (2021)

Article

The potential role of N⁷-methylguanosine (m7G) in cancer

N⁷-methylguanosine (m7G), one of the most prevalent RNA modifications, has recently attracted significant attention. The m7G modification actively participates in biological and pathological functions by affecti....

Yuejun Luo, Yuxin Yao, Peng Wu, **aohui Zi, Nan Sun… in Journal of Hematology & Oncology (2022)

Article

Nivolumab plus ipilimumab: a potential regimen to rewrite treatment guidelines for ESCC

Yuejun Luo, Nan Sun, Jie He in Signal Transduction and Targeted Therapy (2022)

Article

Single-cell analysis reveals the potential mechanisms of pyrotinib resistance in non-small cell lung cancer

**nfeng Wang, Yuan Li, Runsen **, Sufei Zheng… in Signal Transduction and Targeted Therapy (2023)

Article

Costimulatory molecule expression profile as a biomarker to predict prognosis and chemotherapy response for patients with small cell lung cancer

Owing to the paucity of specimens, progress in identifying prognostic and therapeutic biomarkers for small cell lung cancer (SCLC) has been stagnant for decades. Considering that the costimulatory molecules ar...

Peng Wu, Zhihui Zhang, Zhaoyang Yang, Chaoqi Zhang… in Cancer Immunology, Immunotherapy (2023)

Article

A comprehensive pan-cancer analysis of prognostic value and potential clinical implications of FTH1 in cancer immunotherapy

Numerous studies have highlighted the crucial value of the heavy chain of ferritin (FTH1) as a key regulator of iron metabolism and a suppressor of ferroptosis, intimately tied to the tumor immune microenviron...

Yuejun Luo, Chengming Liu, Yuxin Yao, **aoya Tang… in Cancer Immunology, Immunotherapy (2024)