5 Result(s)

Article

Correction: Saikosaponin D exerts antidepressant effect by regulating Homer1-mGluR5 and mTOR signaling in a rat model of chronic unpredictable mild stress

Chen-Yue Liu, Jian-Bei Chen, Yue-Yun Liu, Xue-Ming Zhou, Man Zhang… in Chinese Medicine (2023)

Article

Saikosaponin D exerts antidepressant effect by regulating Homer1-mGluR5 and mTOR signaling in a rat model of chronic unpredictable mild stress

Many studies about depression have focused on the dysfunctional synaptic signaling in the hippocampus that drives the pathophysiology of depression. Radix Bupleuri has been used in China for over 2000 years to re...

Chen-Yue Liu, Jian-Bei Chen, Yue-Yun Liu, Xue-Ming Zhou, Man Zhang… in Chinese Medicine (2022)

Article

**aoyaosan exerts antidepressant-like effects by regulating the functions of astrocytes and EAATs in the prefrontal cortex of mice

Mounting evidence indicates that the cerebral cortex is an important physiological system of emotional activity, and its dysfunction may be the main cause of stress. Glutamate is the primary excitatory neurotr...

Yan Liu, **u-fang Ding, **n-xing Wang… in BMC Complementary and Alternative Medicine (2019)

Article

**aoyaosan exerts anxiolytic-like effects by down-regulating the TNF-α/JAK2-STAT3 pathway in the rat hippocampus

Although the anxiolytic-like effects of **aoyaosan, a Chinese herbal formula, have been described in many previous studies, its underlying mechanism remains undefined. The cytokine tumour necrosis factor-α (TN...

**ao-Juan Li, Qing-Yu Ma, You-Ming Jiang, **ao-Hui Bai, Zhi-Yi Yan… in Scientific Reports (2017)