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    Protocol

    DNA Methylation Analysis

    DNA methylation of promoter CpG islands silences their downstream genes, and enhancer methylation can be associated with decreased or increased gene expression. DNA methylation alterations in normal and diseas...

    Naoko Hattori, Yu-Yu Liu, Toshikazu Ushijima in Inflammation and Cancer (2023)

  2. Article

    Tanshinol alleviates impaired bone formation by inhibiting adipogenesis via KLF15/PPARγ2 signaling in GIO rats

    Glucocorticoid (GC)-induced osteoporosis (GIO) is characterized by impaired bone formation, which can be alleviated by tanshinol, an aqueous polyphenol isolated from Salvia miltiorrhiza Bunge. In this study we...

    Ya-jun Yang, Zhu Zhu, Dong-tao Wang, **n-le Zhang, Yu-yu Liu… in Acta Pharmacologica Sinica (2018)

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  3. Article

    Osteogenic effects of D(+)β-3,4-dihydroxyphenyl lactic acid (salvianic acid A, SAA) on osteoblasts and bone marrow stromal cells of intact and prednisone-treated rats

    Previous studies have shown that D(+)β-3,4-dihydroxyphenyl lactic acid (salvianic acid A, SAA) has anabolic effects on prednisone (GC)-induced osteoporosis in rats. The current study aims to investigate the molec...

    Liao Cui, Yu-yu Liu, Tie Wu, Chun-mei Ai, Huai-qing Chen in Acta Pharmacologica Sinica (2009)

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