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Article
Chemical Constituents from Ampelopsis grossedentata and Their Inhibitory Effects on Th17 Cell Differentiation
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Article
ASH2L upregulation contributes to diabetic endothelial dysfunction in mice through STEAP4-mediated copper uptake
Endothelial dysfunction is a common complication of diabetes mellitus (DM) and contributes to the high incidence and mortality of cardiovascular and cerebrovascular diseases. Aberrant epigenetic regulation und...
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Article
Open AccessLDLR is an entry receptor for Crimean-Congo hemorrhagic fever virus
Crimean-Congo hemorrhagic fever virus (CCHFV) is the most widespread tick-born zoonotic bunyavirus that causes severe hemorrhagic fever and death in humans. CCHFV enters the cell via clathrin-mediated endocyto...
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Article
Open AccessCantharidin suppresses hepatocellular carcinoma development by regulating EZH2/H3K27me3-dependent cell cycle progression and antitumour immune response
Cantharidin (CTD) is a major ingredient of cantharis (Mylabris phalerata Pallas) and has been used extensively in traditional Chinese medicines. It has been shown to exhibit anticancer activity in multiple types ...
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Article
Open AccessEvaluation of career planning group counseling and its effectiveness for intern male nursing students
To investigate the influence of group counselling on the career planning and career maturity of male nursing students.
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Article
Transcription factor Klf9 controls bile acid reabsorption and enterohepatic circulation in mice via promoting intestinal Asbt expression
Bile acid (BA) homeostasis is regulated by the extensive cross-talk between liver and intestine. Many bile-acid-activated signaling pathways have become attractive therapeutic targets for the treatment of meta...
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Article
An epidemiological survey of mental disorders 5 years after the Lushan earthquake in Ya’an, China
This study aimed to (1) explore the prevalence and relevant influencing factors of different mental disorders 5 years after the Lushan earthquake in Ya’an, China.
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Article
Single-block measurement for the cryogenic permanent magnet undulator sorting
The magnet sorting is a standard step in the undulator fabrication procedure. The shortest undulators period used in the High Energy Photon Source (HEPS) is only 12 mm. To the short period undulator, the sorti...
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Article
Synthesis, gas barrier and molecular simulation of intrinsic high-barrier polyimide bearing carbazole and amide
A novel diamine (3,6-CAPDA) bearing carbazole and amide group was prepared. On the basis of 3,6-CAPDA and pyromellitic dianhydride (PMDA), a high-barrier polyimide (3,6-CAPPI) was obtained through a two-step p...
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Article
WSTF acetylation by MOF promotes WSTF activities and oncogenic functions
Williams syndrome transcription factor (WSTF) is a transcription factor and tyrosine kinase. WSTF overexpression promotes migration and proliferation of various cancers, and Ser158 (WSTFS158) phosphorylation play...
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Article
Open AccessIdentification of a novel autoantibody against self-vimentin specific in secondary Sjögren’s syndrome
Sjögren’s syndrome (SS) is a primary autoimmune disease (pSS) or secondarily associated with other autoimmune diseases (sSS). The mechanisms underlying immune dysregulation in this syndrome remain unknown, and...
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Article
Open AccessDiscrimination of Radix Polygoni Multiflori from different geographical areas by UPLC-QTOF/MS combined with chemometrics
Nowadays, Radix Polygoni Multiflori (RPM, Heshouwu in Chinese) from different geographical origins were used in clinic. In order to characterize the chemical profiles of different geographical origins of RPM s...
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Article
Direct growth of bundle-like cobalt selenide nanotube arrays on Ni foam as binder-free electrode for high-performance supercapacitors
Freestanding bundle-like Co0.85Se nanotube arrays on nickle foam were prepared through a facile ion-exchange reaction and directly used as electrodes for supercapacitors. The morphology and structure of the obtai...
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Article
Rock outcrops redistribute water to nearby soil patches in karst landscapes
The emergence of rock outcrops is very common in terrestrial ecosystems. However, few studies have paid attention to their hydrological role in the redistribution of precipitation, especially in karst ecosyste...
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Article
Effects of management on vegetation dynamics and associated nutrient cycling in a karst area, Yunnan, SW China
The legacies of land use (such as plantations, pastures and coppices) in the Shilin karst area of central Yunnan, SW China have strongly influenced the plant communities’ structure, dynamics, species diversity...