-
Article
Open AccessAdolescent suicidal ideation: dissecting the role of sex in depression and NSSI predictors
Suicidal ideation (SI) is increasingly prevalent among adolescents, often arising from depression and linked with non-suicidal self-injury (NSSI). Previous studies have noted significant sex differences in the...
-
Article
Open AccessAcacetin alleviates autoimmune myocarditis by regulating CD4+ T cell mitochondrial respiration
Myocarditis refers to an autoimmune inflammatory response of the myocardium with characterization of self-reactive CD4+ T cell activation, which lacks effective treatment and has a poor prognosis. Acacetin is ...
-
Article
Open AccessMental toughness in adolescents: bridging family relationships and depression across personality traits
Adolescence is a pivotal stage vulnerable to mental health issues like anxiety and depression. While family relationships, mental toughness, and personality traits are known to impact adolescent mental health,...
-
Article
Open AccessPlasma metabolites of aromatic amino acids associate with clinical severity and gut microbiota of Parkinson’s disease
Gut microbial proteolytic metabolism has been reportedly altered in Parkinson’s disease (PD). However, the circulating aromatic amino acids (AAA) described in PD are inconsistent. Here we aimed to investigate ...
-
Article
Open AccessYeast cell detection using fuzzy automatic contrast enhancement (FACE) and you only look once (YOLO)
In contemporary biomedical research, the accurate automatic detection of cells within intricate microscopic imagery stands as a cornerstone for scientific advancement. Leveraging state-of-the-art deep learning...
-
Chapter and Conference Paper
Laser Raman Characteristics of Fluid Inclusions in Chang 7 Shale of Yanchang Formation in **asiwan Exploration Area
In order to reveal the accumulation and enrichment process of continental shale gas, the fluid inclusions in the shale interlayer of Chang 7 member of the Yanchang Formation in the **asiwan exploration area of...
-
Article
Open AccessLow-abundance populations distinguish microbiome performance in plant cell wall deconstruction
Plant cell walls are interwoven structures recalcitrant to degradation. Native and adapted microbiomes can be particularly effective at plant cell wall deconstruction. Although most understanding of biological...
-
Article
Open AccessImproving MGMT methylation status prediction of glioblastoma through optimizing radiomics features using genetic algorithm-based machine learning approach
O6-Methylguanine-DNA-methyltransferase (MGMT) promoter methylation was shown in many studies to be an important predictive biomarker for temozolomide (TMZ) resistance and poor progression-free survival in glio...
-
Article
Open AccessEnhancing predictions of antimicrobial resistance of pathogens by expanding the potential resistance gene repertoire using a pan-genome-based feature selection approach
Predicting which pathogens might exhibit antimicrobial resistance (AMR) based on genomics data is one of the promising ways to swiftly and precisely identify AMR pathogens. Currently, the most widely used geno...
-
Article
Open AccessPangenomeNet: a pan-genome-based network reveals functional modules on antimicrobial resistome for Escherichia coli strains
Discerning genes crucial to antimicrobial resistance (AMR) mechanisms is becoming more and more important to accurately and swiftly identify AMR pathogenic strains. Pangenome-wide association studies (e.g. Sco...
-
Article
Open AccessPhysiologic biomechanics enhance reproducible contractile development in a stem cell derived cardiac muscle platform
Human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs) allow investigations in a human cardiac model system, but disorganized mechanics and immaturity of hPSC-CMs on standard two-dimensional surfaces ha...
-
Article
FDGLib: A Communication Library for Efficient Large-Scale Graph Processing in FPGA-Accelerated Data Centers
With the rapid growth of real-world graphs, the size of which can easily exceed the on-chip (board) storage capacity of an accelerator, processing large-scale graphs on a single Field Programmable Gate Array (...
-
Article
Open AccessCharacterization of TMAO productivity from carnitine challenge facilitates personalized nutrition and microbiome signatures discovery
The capability of gut microbiota in degrading foods and drugs administered orally can result in diversified efficacies and toxicity interpersonally and cause significant impact on human health. Production of a...
-
Article
Combining machine learning models via adaptive ensemble weighting for prediction of shear capacity of reinforced-concrete deep beams
This study presents a novel artificial intelligence (AI) technique based on two support vector machine (SVM) models and symbiotic organisms search (SOS) algorithm, called “optimized support vector machines wit...
-
Article
Prediction of permanent deformation in asphalt pavements using a novel symbiotic organisms search–least squares support vector regression
The prediction of asphalt performance can be very important in terms of increasing service life and performance while saving energy and money. In this study, a new hybrid artificial intelligence (AI) system, S...
-
Article
A self-tuning least squares support vector machine for estimating the pavement rutting behavior of asphalt mixtures
The present study proposes a new self-tuning least squares support vector machine, called MSOS-SVM, for modeling the pavement rutting behavior of asphalt mixtures. MSOS-SVM combines the least squares support v...
-
Article
Skin test of tuberculin purified protein derivatives with a dissolving microneedle-array patch
The tuberculin skin test (TST) is a long-established screening method for tuberculosis. However, the Mantoux technique is often difficult to reliably perform, which affects testing results and safety, which ca...
-
Article
Open AccessMetagenomic, phylogenetic, and functional characterization of predominant endolithic green sulfur bacteria in the coral Isopora palifera
Endolithic microbes in coral skeletons are known to be a nutrient source for the coral host. In addition to aerobic endolithic algae and Cyanobacteria, which are usually described in the various corals and form a...
-
Article
Open AccessStout camphor tree genome fills gaps in understanding of flowering plant genome evolution
We present reference-quality genome assembly and annotation for the stout camphor tree (Cinnamomum kanehirae (Laurales, Lauraceae)), the first sequenced member of the Magnoliidae comprising four orders (Laurales,...
-
Article
Open AccessDevelopment and characterization of stable anaerobic thermophilic methanogenic microbiomes fermenting switchgrass at decreasing residence times
Anaerobic fermentation of lignocellulose occurs in both natural and managed environments, and is an essential part of the carbon cycle as well as a promising route to sustainable production of fuels and chemic...
