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Article
Development of a high-pH reversed-phase well plate for peptide fractionation and deep proteome analysis of cells and exosomes
The complexity of the proteome often limits the number of identified proteins in the nanoflow LC-MS (nanoLC-MS) analysis of samples. Therefore, peptide fractionation is essential for reducing the sample comple...
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Article
Open AccessPleural cytokines MIF and MIP-3α as novel biomarkers for complicated parapneumonic effusions and empyema
Patients with complicated parapneumonic effusion (CPPE)/empyema have high morbidity and mortality, particularly when adequate management is delayed. We aimed to investigate novel dysregulated cytokines that ca...
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Article
Open AccessCombined serum biomarkers in the noninvasive diagnosis of complicated parapneumonic effusions and empyema
We previously demonstrated that the pleural levels of proteins (neutrophil gelatinase-associated lipocalin/NGAL, calprotectin, bactericidal permeability-increasing/BPI, azurocidin 1/AZU-1) were valuable marker...
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Article
Open AccessStout camphor tree genome fills gaps in understanding of flowering plant genome evolution
We present reference-quality genome assembly and annotation for the stout camphor tree (Cinnamomum kanehirae (Laurales, Lauraceae)), the first sequenced member of the Magnoliidae comprising four orders (Laurales,...
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Article
Open AccessProteome profiling reveals novel biomarkers to identify complicated parapneumonic effusions
Patients with pneumonia and parapneumonic effusion (PPE) have elevated mortality and a poor prognosis. The aim of this study was to discover novel biomarkers to help distinguish between uncomplicated PPE (UPPE...