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Article
Open AccessThe Joubert Syndrome Gene arl13b is Critical for Early Cerebellar Development in Zebrafish
Joubert syndrome is characterized by unique malformation of the cerebellar vermis. More than thirty Joubert syndrome genes have been identified, including ARL13B. However, its role in cerebellar development remai...
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Article
Open AccessGenome-wide analysis of light-regulated alternative splicing mediated by photoreceptors in Physcomitrella patens
Light is one of the most important factors regulating plant growth and development. Light-sensing photoreceptors tightly regulate gene expression to control photomorphogenic responses. Although many levels of ...
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Article
A KE-LSA approach for user-centered design
In today’s highly competitive business environment, most successful companies use ‘user-centered’ design techniques, to create products that meet user needs. Designers have used traditional user-centered desig...
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Article
Synthesis and evaluation of N-(2-[18F]fluoro-4-nitrobenzoyl)glucosamine: a preliminary report
d-glucosamine at concentration of certain range could kill tumor cells without influencing normal cells. There are also some reports on the antitumor activity of d-glucosamine and its derivatives in murine models...
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Article
(S)-2-((S)-2-(4-(3-[18F]fluoropropyl)benzamido)-3-phenylpropanamido)pentanedioic acid labeled with 18F
As degradation product of Antineoplaston A10 in vivo, phenylacetyl glutamine showed antitumor activities. According to literatures, we designed and radiosynthesized a phenylacetyl glutamine derivative, which w...