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Article
A conceptually simple and generic construction of plaintext checkable encryption in the standard model
Plaintext-checkable encryption (PCE) can support searches over ciphertext by directly using plaintext. The functionality of a search is modeled by a specific check algorithm that takes a pair of target plainte...
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Article
Increased late-onset glaucoma risk following vitrectomy for macular pucker or hole
The long-term risk of develo** glaucoma after vitrectomy remains uncertain. This retrospective population-based cohort study aimed to explore this risk following vitrectomy for macular pucker or hole.
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Article
Design of a Digital Gamified Learning Activity for Relationship Education with Conceptual Scaffolding and Reflective Scaffolding
To promote motivation and interaction among learners for relationship education in online learning, we designed a digital gamified learning activity for relationship education combined with conceptual and refl...
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Article
Investigation of Eurycoma longifolia Extract on Alleviating Steatosis by Using In Vivo and In Vitro Steatotic Models: Mechanisms Through Activation of AMPK and Autophagic Flux
Eurycoma longifolia Jack, Simaroubaceae, is a popular tropical herb native to Southeast Asia, known for its medicinal properties. This study aimed to determine the inhibitory mechanisms of E. longifolia root extr...
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Article
Open AccessFunctional brain region-specific neural spheroids for modeling neurological diseases and therapeutics screening
3D spheroids have emerged as powerful drug discovery tools given their high-throughput screening (HTS) compatibility. Here, we describe a method for generating functional neural spheroids by cell-aggregation o...
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Article
Design and evaluation of a remote synchronous gamified mathematics teaching activity that integrates multi-representational scaffolding and a mind tool for gamified learning
Gamified learning is an instructional strategy that motivates students to learn, and the use of multiple representations assists learning by promoting students’ thinking and advanced mathematical problem-solvi...
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Article
CD47 blockade improves the therapeutic effect of osimertinib in non-small cell lung cancer
The third-generation epidermal growth factor receptor (EGFR) inhibitor osimertinib (OSI) has been approved as the first-line treatment for EGFR-mutant non-small cell lung cancer (NSCLC). This study aims to exp...
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Chapter and Conference Paper
A Prototype Design on Privacy-Preserving Outsourced Bayesian Network
Recently, cloud computing acts as a significant service for outsourcing some heavy-weight tasks. It also can take care of machine learning, where a trained model can be outsourced to the server, and then a use...
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Article
Bioprinted 3D outer retina barrier uncovers RPE-dependent choroidal phenotype in advanced macular degeneration
Age-related macular degeneration (AMD), a leading cause of blindness, initiates in the outer-blood-retina-barrier (oBRB) formed by the retinal pigment epithelium (RPE), Bruch’s membrane, and choriocapillaris. ...
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Article
Natural history of lung squamous cell brain metastases in patients treated with radiosurgery: a thirty-year experience at a tertiary medical center
In this study we report our 30-year experience in stereotactic radiosurgery (SRS) treatment of lung squamous cell carcinoma (LUSC) brain metastases (BMs). It will serve to provide detailed longitudinal outcome...
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Article
Open AccessModeling SARS-CoV-2 and influenza infections and antiviral treatments in human lung epithelial tissue equivalents
There is a critical need for physiologically relevant, robust, and ready-to-use in vitro cellular assay platforms to rapidly model the infectivity of emerging viruses and develop new antiviral treatments. Here...
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Article
Progress of CD47 immune checkpoint blockade agents in anticancer therapy: a hematotoxic perspective
CD47, a transmembrane protein, acts as a “do not eat me” signal that is overexpressed in many tumor cell types, thereby forming a signaling axis with its ligand signal regulatory protein alpha (SIRPα) and enab...
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Article
Public key encryption with filtered equality test revisited
Without revealing data in the plain, public key encryption with equality test can achieve the basic cryptographic functionalities required. However, the extended version, i.e., public encryption with filtered ...
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Article
Isolating and targeting the real-time plasticity and malignant properties of epithelial-mesenchymal transition in cancer
Epithelial-mesenchymal transition (EMT) is a driving force in promoting malignant cancer, including initiation, growth, and metastasis. EMT is a dynamic process that can undergo a mesenchymal-epithelial transi...
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Article
Open AccessA high-throughput screening to identify small molecules that suppress huntingtin promoter activity or activate huntingtin-antisense promoter activity
Huntington’s disease (HD) is a neurodegenerative disorder caused by a CAG repeat expansion in exon 1 of huntingtin (HTT). While there are currently no disease-modifying treatments for HD, recent efforts have focu...
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Article
Open AccessImprove sample preparation process for miRNA isolation from the culture cells by using silica fiber membrane
In clinical applications of miRNAs, the purity and quality of the testing samples are very critical, especially the obtained tissue sample volume is limited. If the extracted miRNAs are contaminated or differe...
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Article
Open AccessAvian phenotypic convergence is subject to low genetic constraints based on genomic evidence
Phenotypic convergence between distinct species provides an opportunity to examine the predictability of genetic evolution. Unrelated species sharing genetic underpinnings for phenotypic convergence suggests s...
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Article
Open AccessAuthor Correction: Severe Decline of Estimated Glomerular Filtration Rate Associates with Progressive Cognitive Deterioration in the Elderly: A Community-Based Cohort Study
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
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Chapter and Conference Paper
Real-Time Multi-class Instance Segmentation with One-Time Deep Embedding Clustering
In recent years, instance segmentation research has been considered as an extension of object detection and semantic segmentation, which can provide pixel-level annotations on detected objects. Several approa...
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Chapter and Conference Paper
Witness-Based Searchable Encryption with Aggregative Trapdoor
The well-known open problem in public key encryption with keyword search is how to avoid internal adversaries as the server. Implicitly, the internal attack is implemented as follows. Upon receiving a trapdoor...
