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5,062 Result(s)
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Article
Open AccessPassively harmonic dissipative soliton generation in normal dispersion erbium-doped fiber laser using SMS fiber as artificial saturable absorber
Passively harmonic mode-locking has been experimentally demonstrated in an erbium-doped fiber laser with large normal dispersion using single-multi-single mode structure as artificial saturable absorber. By in...
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Open AccessPreoperative neutrophil–to–lymphocyte ratio after chemoradiotherapy for esophageal squamous cell carcinoma associates with postoperative pulmonary complications following radical esophagectomy
Esophagectomy after chemoradiotherapy is associated with an increased risk of surgical complications. The significance of preoperative neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio after chem...
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Open AccessSingle dose of intravenous miR199a-5p delivery targeting ischemic heart for long-term repair of myocardial infarction
Long-term treatment of myocardial infarction is challenging despite medical advances. Tissue engineering shows promise for MI repair, but implantation complexity and uncertain outcomes pose obstacles. microRNA...
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MicroRNA-146a Signature in Psoriasis: A Systematic Review and Meta-Analysis
Psoriasis is a chronic, inflammatory, T-cell-mediated disease with a multifactorial pathogenesis. MicroRNA (miRNA) alteration in psoriasis has been identified within the last few years. In particular, miR-146a...
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miR-141-3p attenuates RSL3-induced ferroptosis and intestinal epithelial-mesenchymal transition via directly inhabits ZEB1 in intestinal Behçet’s syndrome
The aims of this study were to investigate whether the ferroptosis is involved in intestinal Behçet’s syndrome (IBS), and to identify if miR-141-3p could attenuate RAS-selective lethal 3 (RSL3)-induced ferropt...
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Efficiency of PGK1 proteins delivered to the brain via a liposomal system through intranasal route administration for the treatment of spinocerebellar ataxia type 3
A patient-friendly and efficient treatment method for patients with spinocerebellar ataxia type 3 (SCA3) was provided through a nose-to-brain liposomal system. Initially, PGK1 was overexpressed in HEK 293-84Q-...
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Open AccessFamily history and gastric cancer incidence and mortality in Asia: a pooled analysis of more than half a million participants
The family history of gastric cancer holds important implications for cancer surveillance and prevention, yet existing evidence predominantly comes from case–control studies. We aimed to investigate the associ...
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Infrared-responsive shape memory self-healing and fluorescent damage-indication anti-corrosion coatings for aluminum alloys
Widely applied aluminum alloys in ship hulls, underwater vehicles, and marine machinery experience severe corrosion in harsh marine environments. For corrosion protection of aluminum alloys, the most convenien...
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Article
Abnormal phosphorylation / dephosphorylation and Ca2+ dysfunction in heart failure
Heart failure (HF) can be caused by a variety of causes characterized by abnormal myocardial systole and diastole. Ca2+ current through the L-type calcium channel (LTCC) on the membrane is the initial trigger sig...
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Article
Folding angle and wing flexibility influence the flight performance of origami winged fruits
Winged fruits possess a unique flight mechanism relying on simple geometric structures rather than neuromuscular control. This study proposes an innovative approach using origami techniques to create three-win...
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A fine-grained convolutional recurrent model for obstructive sleep apnea detection
Obstructive Sleep Apnea (OSA) is a prevalent sleep-related breathing disorder that leads to various health issues such as hypertension, heart disease, diabetes, and stroke. In order to achieve a convenient, ro...
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Open AccessSpray pyrolysis-derived W-doped MoSe2/rGO paper-like microspheres: optimization of microstructure and mesostructure for enhanced lithium storage
Two-dimensional MoSe2 is a promising candidate for lithium-ion battery anodes. However, its conductivity and lithium storage volumetric effect still need to be optimized. In this work, W-doped MoSe2/rGO paper-lik...
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Open AccessA broad neutralizing nanobody against SARS-CoV-2 engineered from an approved drug
SARS-CoV-2 infection is initiated by Spike glycoprotein binding to the human angiotensin-converting enzyme 2 (ACE2) receptor via its receptor binding domain. Blocking this interaction has been proven to be an ...
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Open AccessEconomic impact of ACES trends on the automotive value chain: a forecast exploratory study of the Chinese automotive industry in 2030
In the context of green transportation, the automotive industry is undergoing a revolution in autonomous, connected, electric, and shared (ACES) vehicles. ACES vehicles have a relatively short history and ther...
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Open AccessCoronin 2B deficiency induces nucleolar stress and neuronal apoptosis
In eukaryotes, the nucleolus is the critical non-membranous organelle within nuclei that is responsible for ribosomal DNA (rDNA) transcription and ribosome biogenesis. The transcription of rDNA, a rate-limitin...
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Open AccessVulnerability factors of snake bite patients in China
To analyze the vulnerability factors of snakebite patients in China.
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Article
Inflammation-Responsive Mesoporous Silica Nanoparticles with Synergistic Anti-inflammatory and Joint Protection Effects for Rheumatoid Arthritis Treatment
Joint destruction is a major burden and an unsolved problem in rheumatoid arthritis (RA) patients. We designed an intra-articular mesoporous silica nanosystem (MSN-TP@PDA-GlcN) with anti-inflammatory and joint...
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Open AccessAdvancing arrhythmia education through the CDIO approach: a new paradigm in nursing student training
The accurate diagnosis and effective management of arrhythmias are crucial, with nurses playing a key role in the early detection and treatment, significantly impacting patient outcomes. Improving education on...
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Open AccessSpatial map** of mobile genetic elements and their bacterial hosts in complex microbiomes
The exchange of mobile genetic elements (MGEs) facilitates the spread of functional traits including antimicrobial resistance within bacterial communities. Tools to spatially map MGEs and identify their bacter...
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Open AccessImpact of repetitive transcranial magnetic stimulation on cortical activity: a systematic review and meta-analysis utilizing functional near-infrared spectroscopy evaluation
Repeated transcranial magnetic stimulation (rTMS) could induce alterations in cortical excitability and promote neuroplasticity. To precisely quantify these effects, functional near-infrared spectroscopy (fNIR...