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Article
Efficacy and Safety of Five Broad-Spectrum Antiseizure Medications for Adjunctive Treatment of Refractory Epilepsy: A Systematic Review and Network Meta-analysis
Overall, up to one-third of epilepsy patients have drug-resistant epilepsy. However, there was previously no meta-analysis to support the guidelines for broad-spectrum antiseizure medication selection for the ...
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Article
Relationship between post-traumatic disorder and posttraumatic growth in COVID-19 home-confined adolescents: The moderating role of self-efficacy
Although the COVID-19 pandemic has been traumatogenic for some people, posttraumatic growth (PTG) outcomes have also been observed. This study examined the PTG in adolescents and the moderating effect of self-...
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Article
Open AccessDeepFLR facilitates false localization rate control in phosphoproteomics
Protein phosphorylation is a post-translational modification crucial for many cellular processes and protein functions. Accurate identification and quantification of protein phosphosites at the proteome-wide l...
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Article
Selenite Ameliorates Cadmium-induced Cytotoxicity Through Downregulation of ROS Levels and Upregulation of Selenoprotein Thioredoxin Reductase 1 in SH-SY5Y Cells
Cadmium (Cd) as a ubiquitous toxic heavy metal in the environment, causes severe hazards to human health, such as cellular stress and organ injury. Selenium (Se) was reported to reduce Cd toxicity and the mech...
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Article
Open AccessRelationship between serum homocysteine, fibrinogen, lipoprotein-a level, and peripheral arterial disease: a dose–response meta-analysis
At present, the relationship between serum homocysteine (Hcy), fibrinogen (FIB), lipoprotein-a (LPa), and PAD is uncertain, and there has been no meta-analysis to establish the dose–response relationship betwe...
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Article
Open AccessComparative anatomical and transcriptomic insights into Vaccinium corymbosum flower bud and fruit throughout development
Blueberry (Vaccinium spp.) is characterized by the production of berries that are smaller than most common fruits, and the underlying mechanisms of fruit size in blueberry remain elusive. V. corymbosum ‘O’Neal’ a...
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Article
Open AccessGram-scale total synthesis of teixobactin promoting binding mode study and discovery of more potent antibiotics
Teixobactin represents a new class of antibiotics with novel structure and excellent activity against Gram-positive pathogens and Mycobacterium tuberculosis. Herein, we report a one-pot reaction to conveniently c...
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Article
Low transcription of CmsIAA9 in the basal pistil is related to parthenocarpic fruiting of fingered citron (Foshou)
Seedlessness is a commercial trait that provides a good model for uncovering fruiting mechanisms. Fingered citron (Citrus medica L. var. sarcodactylis Swingle, Foshou), a variant of Citrus medica L. (**angyuan), ...
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Chapter and Conference Paper
Incorporating User Preferences Across Multiple Topics into Collaborative Filtering for Personalized Merchant Recommendation
Merchant recommendation, namely recommending personalized merchants to a specific customer, has become increasingly important during the past few years especially with the prevalence of Location Based Social N...
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Article
KIPTC: a kernel information propagation tag clustering algorithm
In the social annotation systems, users annotate digital data sources by using tags which are freely chosen textual descriptions. Tags are used to index, annotate and retrieve resource as an additional metadat...
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Article
Prediction of retrotransposons and assessment of genetic variability based on developed retrotransposon-based insertion polymorphism (RBIP) markers in Pyrus L
Interspecific hybridization has been considered the major mode of evolution in Pyrus (pear), and thus, the genetic relationships within this genus have not been well documented. Retrotransposons are ubiquitous co...
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Article
Genetic Diversity and Population Structure of Seedling Populations of Pyrus pashia
Pyrus pashia, described as an intermediate species between oriental and occidental pear groups, is one of the most important wild pears. This study used microsatellite markers at 14 loci to assay...
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Article
Chloroplast DNA-based genetic diversity and phylogeography of Pyrus betulaefolia (Rosaceae) in Northern China
Pyrus betulaefolia Bunge, considered as an intermediate between oriental and occidental pear groups, is one of the most important wild pear species. The number of its populations is decreasing be...
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Article
Open AccessThe importance of biopsy in clinically diagnosed metastatic lesions in patients with breast cancer
Receptor status discordance, such as estrogen receptor (ER), progesterone receptor (PR) and human epidermal growth factor receptor 2 (HER2) status between primary breast cancer and metastatic lesions has been ...
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Article
Development of genic SSR markers from transcriptome sequencing of pear buds
A total of 8375 genic simple sequence repeat (SSR) loci were discovered from a unigene set assembled from 116 282 transcriptomic unigenes in this study. Dinucleotide repeat motifs were the most common with a f...
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Article
C9ORF72 Mutations in Neurodegenerative Diseases
Recent works have demonstrated an expansion of the GGGGCC hexanucleotide repeat in the first intron of chromosome 9 open reading frame 72 (C9ORF72), encoding an unknown C9ORF72 protein, which was responsible for ...
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Chapter and Conference Paper
An Intelligent Search Platform for Business News
Living in a data driven world, the business news is very crucial for making economic decisions. To help decision makers obtain related business news quickly, two kinds of providers for business news, i.e., the...
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Article
A new effective process for production of curdlan oligosaccharides based on alkali-neutralization treatment and acid hydrolysis of curdlan particles in water suspension
Biologically active β-1,3-oligosaccharides with rapidly growing biomedical applications are produced from hydrolysis of curdlan polysaccharide. The water-insoluble curdlan impedes its hydrolysis efficiency whi...
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Chapter and Conference Paper
Mining Frequent Patterns in Print Logs with Semantically Alternative Labels
It is common today for users to print the informative information from webpages due to the popularity of printers and internet. Thus, many web printing tools such as Smart Print and PrintUI are developed for onli...
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Chapter and Conference Paper
A Novel Classification Algorithm to Noise Data
It is a significant challenge to discover knowledge from noise data. Most of previous works have focused on the data cleansing and the correction for the benefit of the subsequent mining process. When the trai...
