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  1. Article

    Open Access

    Prognostic factors in 448 newly diagnosed multiple myeloma receiving bortezomib-based induction: impact of ASCT, transplant refusal and high-risk MM

    In Hong Kong, newly diagnosed multiple myeloma (NDMM) receives bortezomib-based triplet induction. Upfront autologous stem cell transplant (ASCT) is offered to transplant eligible (TE) patients (NDMM ≤ 65 year...

    Hoi Ki Karen Tang, Chi Yeung Fung, Yu Yan Hwang, Harold Lee in Bone Marrow Transplantation (2024)

  2. Article

    Open Access

    Hepatitis B virus reactivation in seronegative occult hepatitis B patient receiving ibrutinib therapy

    Ibrutinib is a Bruton’s tyrosine kinase (BTK) inhibitor approved for the treatment for several mature B-cell malignancies. Reactivation of hepatitis B virus (HBV) is a well-described complication in patients w...

    Lok-Ka Lam, Thomas Sau Yan Chan, Yu-Yan Hwang, Lung-Yi Mak in Virology Journal (2023)

  3. No Access

    Article

    Eltrombopag as frontline treatment of aplastic anaemia in routine practice: implications on cost and efficacy

    The thrombopoietin mimetic eltrombopag (EPAG) is efficacious in clinical trials of newly diagnosed moderate (M), severe (S) and very severe (vS) aplastic anaemia (AA). Its use in routine practice and resource-...

    Yu-Yan Hwang, Thomas S. Y. Chan, Florence H. Y. Chan in Annals of Hematology (2022)

  4. No Access

    Article

    Epstein-Barr virus–positive diffuse large B-cell lymphoma after frontline brentuximab vedotin treatment of classical Hodgkin lymphoma

    Eric Tse, Rex Au-Yeung, David Chau, Yu-Yan Hwang, Florence Loong in Annals of Hematology (2022)

  5. No Access

    Article

    Ruxolitinib in the management of steroid-resistant/-dependent acute and chronic graft-versus-host disease: results of routine practice in an academic centre

    Graft-versus-host disease (GVHD) is an important complication after allogeneic haematopoietic stem cell transplantation (HSCT). Corticosteroids are the standard first-line treatment. Steroid-resistant/-depende...

    Garret M. K. Leung, Joycelyn P. Y. Sim, Yu-Yan Hwang in Annals of Hematology (2022)

  6. No Access

    Article

    Spectrum of B-cell neoplasms associated with immunoglobulin G4-related disease

    Immunoglobulin G4-related disease (IgG4-RD) has rarely been associated with lymphoid neoplasms, the spectrum of which remains unclear. B-cell lymphoid neoplasms (LN) associated with IgG4-RD diagnosed in a 4-ye...

    Ryan C. W. Ho, Thomas S. Y. Chan, Rex Au-Yeung, Karen H. K. Tang in Annals of Hematology (2022)

  7. No Access

    Article

    Thrombotic thrombocytopenic purpura as the presenting feature of human herpesvirus 6 myocarditis

    Yu-Yan Hwang, Rock Y. Y. Leung, Gavin S. W. Chan, Cyril C. Y. Yip in Annals of Hematology (2021)

  8. No Access

    Article

    Endocrine complications in patients with transfusion-dependent thalassaemia after haemopoietic stem cell transplantation

    Wing-shan Queenie See, Joanna Yuet-ling Tung in Bone Marrow Transplantation (2018)

  9. No Access

    Article

    Complete response of age-related Epstein-Barr virus-associated polymorphic nodal lymphoproliferative disease of plasmacytic type to low-dose lenalidomide

    Yu-Yan Hwang, Rex Au-Yeung, Hon-Pang Lau, Yok-Lam Kwong in Annals of Hematology (2018)

  10. No Access

    Article

    Low-dose nivolumab induced remission in refractory classical Hodgkin lymphoma

    Yu-Yan Hwang, Pek-Lan Khong, Yok-Lam Kwong in Annals of Hematology (2017)

  11. No Access

    Article

    Cytomegalovirus retinitis complicating combination therapy with rituximab and fludarabine

    Cytomegalovirus (CMV) retinitis is exceptionally rare outside the clinical context of acquired immunodeficiency syndrome and organ allografting. In a population where seropositivity for past CMV infection exce...

    Thomas S. Y. Chan, Carol Y. M. Cheung, Ian Y. L. Yeung in Annals of Hematology (2015)

  12. No Access

    Article

    Unilateral hearing loss due to lymphocytosis and a contralateral putamen lesion

    Hilda Wong, Yu-Yan Hwang, Rock Y. Y. Leung, Gavin S. W. Chan in Annals of Hematology (2015)

  13. No Access

    Article

    Breakthrough invasive fungal diseases during echinocandin treatment in high-risk hospitalized hematologic patients

    The frequency of breakthrough invasive fungal diseases (IFDs) during echinocandin therapy is unclear. We retrospectively analyzed 534 hematologic patients treated with echinocandin (caspofungin, N = 55; micafungi...

    Thomas S. Y. Chan, Harinder Gill, Yu-Yan Hwang, Joycelyn Sim in Annals of Hematology (2014)

  14. Article

    Open Access

    Histiocytic sarcoma simulating immune thrombocytopenic purpura

    Joycelyn Sim, Yu-Yan Hwang, Rock Y. Y. Leung, Jason C. C. So in Annals of Hematology (2013)

  15. Article

    Open Access

    Disseminated Langerhans cell histiocytosis associated with acute myeloid leukaemia: complete remission with daunorubicin and cytarabine

    Yu-Yan Hwang, Po Tsui, Rock Y. Y. Leung, Yok-Lam Kwong in Annals of Hematology (2013)

  16. Article

    Open Access

    Primary immune thrombocytopenia responding to antithyroid treatment in a patient with Graves’ disease

    Harinder Gill, Yu-Yan Hwang, Eric Tse in Annals of Hematology (2011)

  17. No Access

    Article

    Post-rituximab Burkitt transformation of PTLD: loss of CD20 expression accompanied by a switch in light-chain expression

    Yu-Yan Hwang, Kai Y. Wong, Rock Y. Y. Leung, Simon H. M. Wong in Annals of Hematology (2010)

  18. Article

    Author reply: Bortezomib and restoration of chemosensitivity

    Chor Sang Chim, Yu Yan Hwang, Clara Pang, Tony W. Shek in Nature Reviews Clinical Oncology (2009)

  19. No Access

    Article

    Restoration of chemosensitivity by bortezomib: implications for refractory myeloma

    Resistance to chemotherapy remains one of the major challenges in the treatment of patients with multiple myeloma. Chim et al. report the case of a 59-year-old woman with multiple myeloma, who progressed after tr...

    Chor Sang Chim, Yu Yan Hwang, Clara Pang, Tony W. Shek in Nature Reviews Clinical Oncology (2009)