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Article
An instance of homicide by electrocution with hand-made electrode plates
Homicide by electrocution is rare in forensics, and the identification of the cause of death can be quite difficult when the electric device is removed from the scene. We present an instance where the police w...
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Article
Open AccessProteomic profiling of sudden cardiac death with acquired cardiac hypertrophy
Cardiac hypertrophy, which develops in middle-aged and older individuals as a consequence of hypertension and obesity, is an established risk factor for sudden cardiac death (SCD). However, it is sometimes dif...
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Article
Open AccessCorrelation of cytomegalovirus viral load between whole blood and plasma of congenital cytomegalovirus infection under valganciclovir treatment
Congenital cytomegalovirus (CMV) infection (cCMV) can cause sensorineural hearing loss and neurodevelopmental disabilities in children. Oral valganciclovir (VGCV) therapy has been reported to improve long-term...
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Article
Open AccessGastric aspiration in sudden unexpected infant death of Prader–Willi syndrome: immunohistochemical detection of feeding components
Prader–Willi syndrome (PWS) in infants is characterized by hypotonia and poor sucking with feeding difficulties. Two autopsy cases of sudden unexpected death during sleep after tube feeding are described herei...
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Article
A survey of solitary death by heat stroke in Yokohama City
Recent global warming and the progression of the heat-island phenomenon, mainly in urban areas, have increased the risk of heat stroke development throughout Japan. Consequently, the risk of solitary death due...
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Article
Nonocclusive mesenteric ischemia secondary to spinal cord injury: an autopsy case
Spinal cord injury (SCI) is a major direct cause of accidental death. Cervical SCI can lead to death in a short time period by neurogenic shock. Prompt vasopressor administration is recommended for patients wi...
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Article
MicroRNA profiling of gastric content from breast-fed and formula-fed infants to estimate last feeding: a pilot study
Recently, we were consulted about a challenging case, where an infant died by poisoning and the drug-dependent mother insisted that she unintentionally gave the toxic drug through breast milk. Accordingly, we ...
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Article
Open AccessHierarchical Cluster and Region of Interest Analyses Based on Mass Spectrometry Imaging of Human Brain Tumours
Imaging mass spectrometry (IMS) has been rarely used to examine specimens of human brain tumours. In the current study, high quality brain tumour samples were selected by tissue observation. Further, IMS analy...
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Article
Open AccessThe importance of the rate of pure “attended deaths at home” for objective outcome indicator for assessing the prevalence of home care in Japan
No study has yet been performed on the importance of the rate of pure “attended deaths at home,” excluding examined deaths subjected to a postmortem examination. Therefore, in the present study, we investigate...
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Article
Open AccessMyocardial lipofuscin accumulation in ageing and sudden cardiac death
Lipofuscin is an intracellular aggregate of highly oxidized proteins that cannot be digested in the ubiquitin-proteasome system and accumulate mainly in lysosomes, especially in aged cells and pathological con...
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Article
Open AccessA descriptive study of solitary death in Yokohama City
The solitary death rate in Japan is expected to continue increasing because of its growing super-aged society and the rapid growth of home care in the country. To accurately determine the actual status of soli...
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Article
Open AccessRegion of Interest analysis using mass spectrometry imaging of mitochondrial and sarcomeric proteins in acute cardiac infarction tissue
Matrix-assisted laser desorption ionization image mass spectrometry (MALDI-IMS) has been developed for the identification of peptides in various tissues. The MALDI-IMS signal distribution patterns and quantifi...
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Article
Combined effects of multiple linked loci on pairwise sibling tests
The advanced multiplex STR system, PowerPlex Fusion, includes four linked locus pairs. The conventional Identifiler system has one pair of linked loci. Therefore, sibling tests conducted using the advanced sys...
