-
Article
Optimization of riboflavin production by recombinant Bacillus subtilis RH44 using statistical designs
A sequential optimization strategy, based on statistical experimental designs, was used to enhance the production of riboflavin by recombinant Bacillus subtilis RH44. In the first instance, the medium components ...
-
Article
Enhanced Delivery of Erythropoietin Across the Blood–Brain Barrier for Neuroprotection Against Ischemic Neuronal Injury
Due to limited penetration of the blood–brain barrier (BBB), many therapeutic agents in clinical use require higher doses in order to reach effective concentrations in brain. In some instances, these high dose...
-
Article
Sequence-selective assembly of tweezer molecules on linear templates enables frameshift-reading of sequence information
Information storage and processing is carried out at the level of individual macromolecules in biological systems, but there is no reason, in principle, why synthetic copolymers should not be used for the same...
-
Protocol
Biochemical and Molecular Biological Assessments of Global Cerebral Ischemia: mRNA
DNA microarrays have indicated that significant gene expression changes following global cerebral ischemia occur, and that neurotherapeutic strategies may specifically impact RNA expression in ischemic cells. ...
-
Article
Two-stage orbital order and dynamical spin frustration in KCuF3
Orbital order is important to many correlated electron phenomena, including colossal magnetoresistance and high-temperature superconductivity. A study of a previously unreported structure transition in KCuF3 sugg...
-
Protocol
Biochemical and Molecular Biological Assessments of Focal Cerebral Ischemia: Protein
Focal cerebral ischemia induces a complex array of cellular states, which significantly influence and ultimately are controlled by molecular changes. While certainly some of these changes occur at the nucleoti...
-
Protocol
Biochemical and Molecular Biological Assessments of Global Cerebral Ischemia: Protein
The evaluation of protein expression and modifications following global cerebral ischemia has led to better characterization of selectively vulnerable neuronal populations and exploration of potential targets ...
-
Protocol
Biochemical and Molecular Biological Assessments of Focal Cerebral Ischemia: mRNA and MicroRNA
Evaluation of messenger RNA (mRNA) expression has long been used as evidence demonstrating alterations in gene expression at the transcriptional level following global ischemia. Given the complexity of focal c...
-
Article
Lack of association between miR-149 C>T polymorphism and cancer susceptibility: a meta-analysis based on 4,677 cases and 4,830 controls
To derive a more precise estimation of the relationship between miR-149 C>T polymorphism and cancer risk, a meta-analysis was performed. A total of 8 studies including 4,677 cases and 4,830 controls were involved...
-
Chapter and Conference Paper
EMD De-Noising Theory Considering Static and Dynamic Conditions and Its Applications in INS
De-noising IMU data is an important approach to improve the accuracy of INS. Wavelet threshold de-noising has many limitations under certain conditions, especially in processing inertial sensor errors. Based o...
-
Chapter and Conference Paper
An Improved Algorithm for Single Point Positioning of COMPASS
The BeiDou (COMPASS) Navigation Satellite System has been able to provide service for areas in China and its surrounding areas. However, due to the limited number of satellites and the low accuracy, its applic...
-
Article
Current evidence on the relationship between three polymorphisms in the XRCC7 gene and cancer risk
Inconsistency of the association of polymorphisms of XRCC7 with cancer is noted. Three commonly studied XRCC7 polymorphisms including rs7003908 (T>G), rs7830743 (A>G), and rs10109984 (T>C) were selected to explor...
-
Article
Vinorelbine and capecitabine in anthracycline- and/or taxane-pretreated metastatic breast cancer: sequential or combinational?
The difference between combinational and pre-planned sequential therapies using regimens that include non-anthracycline and taxane in the first-line setting remains unclear. The purpose of this study is to exp...
-
Chapter
How Do Subcellular Organelles Participate in Preconditioning-Conferred Neuroprotection?
Preconditioning or tolerance is a natural phenomenon of endogenous adaptation, whereby subtoxic stress protects against subsequent higher dose stress. Although preconditioning is likely to be a ubiquitous stre...
-
Article
PIK3CA mutation is associated with poor survival among patients with metastatic colorectal cancer following anti-EGFR monoclonal antibody therapy: a meta-analysis
PIK3CA mutation appears to predict a lack of response to anti-EGFR monoclonal antibody (mAb) treatment in patients with metastatic colorectal cancer (mCRC). However, the predictive value of PIK...
-
Article
Optimal forwarding ratio on dynamical networks with heterogeneous mobility
Since the discovery of non-Poisson statistics of human mobility trajectories, more attention has been paid to understand the role of these patterns in different dynamics. In this study, we first introduce the ...
-
Chapter
The Critical Roles of Immune Cells in Acute Brain Injuries
Acute brain injuries elicit prompt and robust immune responses characterized by the activation of local glial cells and mobilization of peripheral leukocytes. The activation of immune cells originally aims to ...
-
Article
Association of obesity and overweight with overall survival in colorectal cancer patients: a meta-analysis of 29 studies
Previous studies that assessed the relationship between obesity, overweight, and survival in colorectal cancer (CRC) have provided conflicting results. Therefore, we quantitatively summarized existing evidence...
-
Chapter and Conference Paper
Refining of BDS Differential Code Bias Model
The differential code bias (DCB) in Global Navigation Satellite System (GNSS) satellites should be precisely determined using real ground GNSS data when designing certain applications, such as precise position...
-
Chapter and Conference Paper
Unscented Kalman Filter Algorithm with Colored Noise and Its Application in Spacecraft Attitude Estimation
The accuracy and reliability of the estimation and prediction of satellite attitude are affected by not only the random noise and systematic errors, but also the colored noise related to time. Any theory or te...
