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Article
Open AccessNavigating the complexity of p53-DNA binding: implications for cancer therapy
The tumor suppressor protein p53, a transcription factor playing a key role in cancer prevention, interacts with DNA as its primary means of determining cell fate in the event of DNA damage. When it becomes mu...
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Open AccessEvaluating Human-Care Robot Services for the Elderly: An Experimental Study
The increase in elderly population is emerging as a serious social issue. The coronavirus pandemic has increased the number of elderly people suffering from depression and loneliness owing to the lack of face-...
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Open AccessEffective theory approach for axion wormholes
We employ the effective field theory approach to analyze the characteristics of Euclidean wormholes within axion theories. Using this approach, we obtain non-perturbative instantons in various complex scalar m...
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Automatic cancer nuclei segmentation on histological images: comparison study of deep learning methods
Cancer is one of the most common health problems affecting individuals worldwide. In the field of biomedical engineering, one of the main methods for cancer diagnosis is the analysis of histological images of ...
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Effect of mesophase formation from quinoline insoluble-containing coal tar pitch on physical properties of carbon blocks
In the present study, a coal-based pitch containing 12.1% quinoline insoluble (QI) underwent isothermal heat treatment, and changes in the mesophase microstructure were analyzed for the heat treatment duration...
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Open AccessTemozolomide promotes matrix metalloproteinase 9 expression through p38 MAPK and JNK pathways in glioblastoma cells
Glioblastoma (GBM) is a highly aggressive and deadly brain cancer. Temozolomide (TMZ) is the standard chemotherapeutic agent for GBM, but the majority of patients experience recurrence and invasion of tumor ce...
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Open AccessChip collection of hepatocellular carcinoma based on O2 heterogeneity from patient tissue
Hepatocellular carcinoma frequently recurs after surgery, necessitating personalized clinical approaches based on tumor avatar models. However, location-dependent oxygen concentrations resulting from the dual ...
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Development of a Real-Time Anomaly Detection System for Dry Vacuum Pumps Using Low-Cost IoT Devices and Machine Learning
Data-driven health diagnosis methods based on machine learning have been receiving a lot of attention with the hope that they can open a new era for mechanical researchers and engineers. Machine learning algor...
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Human adipose-derived stem cells genetically programmed to induce necroptosis for cancer immunotherapy
Herein, we present human adipose-derived stem cells (ADSCs) inserted with the receptor-interacting protein kinase-3 (RIP3) gene (RP@ADSCs), which induces cell necroptosis, for tumor immunotherapy. Necroptosis ...
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Color coherence-based scene-change detection for frame rate up-conversion
Existing scene-change detection methods usually use the differences in luminance values between consecutive frames to detect scene changes. Therefore, they can have difficulty detecting scene changes for vario...
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Open AccessExtraction of the outer membrane protein pertactin from Bordetella pertussis with urea for the production of acellular pertussis vaccine
Pertactin (PRN), a non-fimbrial outer membrane protein of Bordetella pertussis, is the limiting component of the acellular pertussis vaccine because of its low concentration. This study aimed to develop a large-s...
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On the Decidability of Infix Inclusion Problem
We introduce the infix inclusion problem of two languages S and T that decides whether or not S is a subset of the set of all infixes of T. This problem is motivated by the need for identifying malicious computat...
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Electrodeposited Hierarchical Silver Network Transparent Conducting Electrodes with Excellent Optoelectronic Properties and Mechanical Flexibility
Mechanically flexible transparent conductive electrodes (TCEs) with high optoelectronic performance are essential for flexible or wearable optoelectronic devices, which are currently receiving a considerable a...
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Development of Deep Learning Color Recognition Model for Color Measurement Processes
We present a deep learning color recognition model for the color measurement process in the paint industry. Currently, spectrophotometers are primarily used for color measurements owing to their accuracy. The ...
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Open AccessSafety and efficacy of fluoroscopy-guided urethral catheterization in case of failed blind or cystoscopy-assisted urethral catheterization
This retrospective study evaluated the safety and efficacy of fluoroscopy-guided urethral catheterization in patients who failed blind or cystoscopy-assisted urethral catheterization. We utilized our instituti...
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Physics-inspired geophysical assessment of liquefaction potential in Pohang, South Korea
This study aims to assess the liquefaction potential of soil deposits where soil boiling and liquefaction have been first observed since the Pohang earthquake in 2017. We use multi-physics techniques for site ...
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Open AccessEffect of Rim and Web Thickness on Tooth Root Stress of Spur Gear
This study investigated the impact of spur gear rim and web thickness on root stress. A finite-element analysis model (FEM) was utilized and validated through a gear-bending test. Four gears with different rim...
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Open AccessTranscriptome-based deep learning analysis identifies drug candidates targeting protein synthesis and autophagy for the treatment of muscle wasting disorder
Sarcopenia, the progressive decline in skeletal muscle mass and function, is observed in various conditions, including cancer and aging. The complex molecular biology of sarcopenia has posed challenges for the...
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Open AccessBio-inspired “Self-denoising” capability of 2D materials incorporated optoelectronic synaptic array
In in-sensor image preprocessing, the sensed image undergoes low level processing like denoising at the sensor end, similar to the retina of human eye. Optoelectronic synapse devices are potential contenders f...
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Open AccessEffectiveness of Biological Mortars with Bacterial Glycocalyx on Service Life of Concrete Structures Exposed to Salt Attack
This study investigated the effectiveness and limitations of newly developed biological mortars regarding chloride ion diffusion resistance. Through several tests on the glycocalyx production capacity and grow...
