2,886 Result(s)

Article

Chromosome-level genome assembly of Korean holoparasitic plants, Orobanche coerulescens

Orobanche coerulescens is a parasitic plant that cannot complete its life cycle without a host and is incapable of photosynthesis. The habitats of O. coerulescens span the coasts of Korea and its volcanic islands...

Bongsang Kim, So Yun Jhang, Bomin Koh, Soonok Kim, Won-Jae Chi… in Scientific Data (2024)

Article

Automated eyeball volume measurement based on CT images using neural network-based segmentation and simple estimation

With the increase in the dependency on digital devices, the incidence of myopia, a precursor of various ocular diseases, has risen significantly. Because myopia and eyeball volume are related, myopia progressi...

Sujeong Han, Jeong Kyu Lee, Daewon Lee, Jaesung Lee in Scientific Reports (2024)

Article

Hemodialysis-induced positional changes in lamina cribrosa

This study is aimed to investigate the effect of hemodialysis (HD) on the lamina cribrosa (LC) of the optic nerve head (ONH) using swept-source optical coherence tomography (SS-OCT) and other ophthalmological ...

Ji Hong Kim, Hyo Chan Jeong, Yong Un Shin, Won June Lee in Scientific Reports (2024)

Article

Strain-graded quantum dots with spectrally pure, stable and polarized emission

Structural deformation modifies the bandgap, exciton fine structure and phonon energy of semiconductors, providing an additional knob to control their optical properties. The impact can be exploited in colloid...

Dongju Jung, Jeong Woo Park, Sejong Min, Hak June Lee, ** Su Park… in Nature Communications (2024)

Article

Comparison of digital and analog [⁶⁸Ga]Ga-PSMA-11 PET/CT for detecting post-prostatectomy biochemical recurrence in prostate cancer patients: a prospective study

Digital positron emission tomography/computed tomography (PET/CT) has shown enhanced sensitivity and spatial resolution compared with analog PET/CT. The present study compared the diagnostic performance of dig...

Yong-il Kim, Dong Yun Lee, Changhwan Sung, Sang Ju Lee, Seung Jun Oh… in Scientific Reports (2024)

Article

Limited impact of bacterial virulence on early mortality risk factors in Acinetobacter baumannii bacteremia observed in a Galleria mellonella model

Acinetobacter baumannii (AB) has emerged as a major pathogen in vulnerable and severely ill patients. It remains unclear whether early mortality (EM) due to AB bacteremia is because of worse clinical characterist...

Sin Young Ham, June Young Chun, Kyoung-Ho Song, Chang Kyung Kang… in Scientific Reports (2024)

Article

ECMO is associated with decreased hospital mortality in COVID-19 ARDS

This study determined whether compared to conventional mechanical ventilation (MV), extracorporeal membrane oxygenation (ECMO) is associated with decreased hospital mortality or fibrotic changes in patients wi...

Won-Young Kim, Sun-Young Jung, Jeong-Yeon Kim, Ganghee Chae… in Scientific Reports (2024)

Article

Deep learning model integrating cfDNA methylation and fragment size profiles for lung cancer diagnosis

Detecting aberrant cell-free DNA (cfDNA) methylation is a promising strategy for lung cancer diagnosis. In this study, our aim is to identify methylation markers to distinguish patients with lung cancer from h...

Minjung Kim, Juntae Park, Seonghee Oh, Byeong-Ho Jeong, Yuree Byun… in Scientific Reports (2024)

Article

Divergent landscapes of A-to-I editing in postmortem and living human brain

Adenosine-to-inosine (A-to-I) editing is a prevalent post-transcriptional RNA modification within the brain. Yet, most research has relied on postmortem samples, assuming it is an accurate representation of RN...

Miguel Rodriguez de los Santos, Brian H. Kopell… in Nature Communications (2024)

Article

Digital symbol-digit modalities test with modified flexible protocols in patients with CNS demyelinating diseases

Cognitive impairment (CI) is prevalent in central nervous system demyelinating diseases, such as multiple sclerosis (MS) and neuromyelitis optica spectrum disorders (NMOSD). We developed a novel tablet-based m...

Dayoung Seo, Jeong Min So, Jiyon Kim, Heejae Jung, Inhye Jang… in Scientific Reports (2024)

Article

Identification and characterization of plasma proteins associated with intra-amniotic inflammation and/or infection in women with preterm labor

This study aimed to identify plasma proteins that could serve as potential biomarkers for microbial invasion of the amniotic cavity (MIAC) or intra-amniotic inflammation (IAI) in women with preterm labor (PTL)...

Hee Young Cho, Ji Eun Lee, Kyo Hoon Park, Bo Young Choi, Min Jung Lee… in Scientific Reports (2024)

Article

Enhanced osteogenesis of mesenchymal stem cells encapsulated in injectable microporous hydrogel

Delivery of therapeutic stem cells to treat bone tissue damage is a promising strategy that faces many hurdles to clinical translation. Among them is the design of a delivery vehicle which promotes desired cel...

Seth D. Edwards, Mrinal Ganash, Ziqiang Guan, Jeil Lee, Young Jo Kim… in Scientific Reports (2024)

Article

Effect of apigetrin in pseudo-SARS-CoV-2-induced inflammatory and pulmonary fibrosis in vitro model

SARS-CoV-2 has become a global public health problem. Acute respiratory distress syndrome (ARDS) is the leading cause of death due to the SARS-CoV-2 infection. Pulmonary fibrosis (PF) is a severe and frequentl...

Hengmin Han, Jung-Eun Kim, Hyo-Jeong Lee in Scientific Reports (2024)

Article

Assessment of TP53 and CDKN2A status as predictive markers of malignant transformation of sinonasal inverted papilloma

The mechanism and predictive biomarkers of sinonasal inverted papilloma (IP) transformation into squamous cell carcinoma (SCC) are still unclear. We investigated the genetic mutations involved and the predicti...

Soohyeon Kwon, Jeong-Whun Kim, Eun Sun Kim, ** Ho Paik… in Scientific Reports (2024)

Article

Structural insights into GABA_A receptor potentiation by Quaalude

Methaqualone, a quinazolinone marketed commercially as Quaalude, is a central nervous system depressant that was used clinically as a sedative-hypnotic, then became a notorious recreational drug in the 1960s-8...

Weronika Chojnacka, **feng Teng, Jeong Joo Kim, Anders A. Jensen… in Nature Communications (2024)

Article

Publisher Correction: Antioxidant effects of phenolic compounds in through the distillation of Lonicera japonica & Chenpi extract and anti-inflammation on skin keratinocyte

Hun Hwan Kim, Se Hyo Jeong, Min Yeong Park, Pritam Bhangwan Bhosale… in Scientific Reports (2024)

Article

Chip collection of hepatocellular carcinoma based on O₂ heterogeneity from patient tissue

Hepatocellular carcinoma frequently recurs after surgery, necessitating personalized clinical approaches based on tumor avatar models. However, location-dependent oxygen concentrations resulting from the dual ...

Sewoom Baek, Hyun-Su Ha, Jeong Su Park, Min Jeong Cho… in Nature Communications (2024)

Article

Enhancing liver cirrhosis varices and CSPH risk prediction with spleen stiffness measurement using 100-Hz probe

Managing complications of liver cirrhosis such as varices needing treatment (VNT) and clinically significant portal hypertension (CSPH) demands precise and non-invasive diagnostic methods. This study assesses ...

Jeong-Ju Yoo, Sun Ah Maeng, Young Chang, Sae Hwan Lee… in Scientific Reports (2024)

Article

Notum regulates the cusp and root patterns in mouse molar

Notum is a direct target of Wnt/β-catenin signaling and plays a crucial role as a Wnt inhibitor within a negative feedback loop. In the tooth, Notum is known to be expressed in odontoblasts, and severe dentin def...

Dinuka Adasooriya, Ju-Kyung Jeong, Minjae Kyeong, Shiqi Kan… in Scientific Reports (2024)

Article

Octupole moment driven free charge generation in partially chlorinated subphthalocyanine for planar heterojunction organic photodetectors

In this study, high-performance organic photodetectors are presented which utilize a pristine chlorinated subphthalocyanine photoactive layer. Optical and optoelectronic analyses indicate that the device photo...

Aniket Rana, Song Yi Park, Chiara Labanti, Feifei Fang… in Nature Communications (2024)