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Open AccessPapillae alterations around single-implant restorations in the anterior maxillae: thick versus thin mucosa
To evaluate the papilla alterations around single-implant restorations in the anterior maxillae after crown attachment and to study the influence of soft tissue thickness on the papilla fill alteration. Accord...
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Article
Open AccessCharacterization of Fam20C expression in odontogenesis and osteogenesis using transgenic mice
Our previous studies have demonstrated that Fam20C promotes differentiation and mineralization of odontoblasts, ameloblasts, osteoblasts and osteocytes during tooth and bone development. Ablation of the Fam20C ge...
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Article
Open AccessThe role of microRNAs in bone remodeling
Bone remodeling is balanced by bone formation and bone resorption as well as by alterations in the quantities and functions of seed cells, leading to either the maintenance or deterioration of bone status. The...
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Article
Open AccessEffect of anti-biofilm glass–ionomer cement on Streptococcus mutans biofilms
Dental restorative materials with antimicrobial properties can inhibit bacterial colonization, which may result in a reduction of caries at tooth-filling interaction zones. This study aimed to develop antibact...
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Article
Open AccessDental implants and grafting success remain high despite large variations in maxillary sinus mucosal thickening
Although mucosal thickening is the most common radiographic finding observed regarding sinus pathology, the knowledge regarding its clinical significance on the outcomes of dental implants and grafting in the ...
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Article
Open AccessIn silico identification of potential inhibitors targeting Streptococcus mutans sortase A
Dental caries is one of the most common chronic diseases and is caused by acid fermentation of bacteria adhered to the teeth. Streptococcus mutans (S. mutans) utilizes sortase A (SrtA) to anchor surface proteins ...
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Open AccessQuaternary ammonium-induced multidrug tolerant Streptococcus mutans persisters elevate cariogenic virulence in vitro
Dental caries are the most prevalent chronic infections in the oral cavity, and Streptococcus mutans acts as the main cariogenic bacterial species. Antibacterial quaternary ammonium compounds (QAs) have been deve...
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Article
Open AccessAnalysis of differential expression of tight junction proteins in cultured oral epithelial cells altered by Porphyromonas gingivalis, Porphyromonas gingivalis lipopolysaccharide, and extracellular adenosine triphosphate
Tight junctions (TJs) are the most apical intercellular junctions of epithelial cells formed by occludin, claudins, junctional adhesion molecules (JAMs), and zonula occludens (ZO). Tight junction proteins can ...
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Article
Open AccessEffect of surface removal following bleaching on the bond strength of enamel
A reduction in bond strength of bleached enamel has been confirmed in the literature. Although limited information is available, it is conceivable that the veneer preparation process may remove the impacted en...
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Article
Open Access1,25-dihydroxyvitamin D3 suppresses lipopolysaccharide-induced interleukin-6 production through aryl hydrocarbon receptor/nuclear factor-κB signaling in oral epithelial cells
Antiinflammatory effect of 1,25-dihydroxyvitamin D3 (1,25D3) has been reported in periodontitis, but the exact mechanisms remain unclear. Oral epithelial cells are recently highlighted as an important regulator o...
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Article
Open AccessAssociation between tooth loss and hypertension among older Chinese adults: a community-based study
The purpose of the study is to examine the association between tooth loss and hypertension among older community residents in urban China.
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Article
Open AccessCyclic compression emerged dual effects on the osteogenic and osteoclastic status of LPS-induced inflammatory human periodontal ligament cells according to loading force
Appropriate mechanical stimulation is essential for bone homeostasis in healthy periodontal tissues. While the osteogenesis and osteoclast differentiation of inflammatory periodontal ligament cells under diffe...
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Article
Open AccessHigh expression of ACE2 receptor of 2019-nCoV on the epithelial cells of oral mucosa
It has been reported that ACE2 is the main host cell receptor of 2019-nCoV and plays a crucial role in the entry of virus into the cell to cause the final infection. To investigate the potential route of 2019-...
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Open AccessRANKL blockade alleviates peri-implant bone loss and is enhanced by anti-inflammatory microRNA-146a through TLR2/4 signaling
The present study was to determine the effect of local anti-RANKL antibody administration in the presence or absence of microRNA-146a on ligature-induced peri-implant bone resorption, and the potential role of...
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Article
Open AccessKnowledge of and attitudes towards erosive tooth wear among students of two Chinese universities
To assess the knowledge of and attitudes towards erosive tooth wear among dental, medical, and non-medical university students of two Chinese universities.
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Article
Open AccessThe association between denture self-satisfaction rates and OHRQoL - a follow-up study
The objectives of this study were to try to identify the key dimension in satisfaction from the combination of satisfaction clusters, and its effect on the change of OHRQoL(Oral Health-related Quality of Life)...
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Article
Open AccessDeep learning-based dental plaque detection on primary teeth: a comparison with clinical assessments
Dental plaque causes many common oral diseases (e.g., caries, gingivitis, and periodontitis). Therefore, plaque detection and control are extremely important for children’s oral health. The objectives of this ...
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Article
COVID-19: a novel coronavirus and a novel challenge for oral healthcare
Explore how to manage oral healthcare during the COVID-19 outbreak.
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Open AccessEffects of remaining dentin thickness on the bond strength of bleached dentin
The bond strength of resin composites to dentin was reported to be related to either the remaining dentin thickness (RDT) or bleaching treatment. However, information is limited regarding the effects of RDT on...
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Article
Open AccessEfficacy evaluation of photodynamic therapy for oral lichen planus: a systematic review and meta-analysis
Photodynamic therapy (PDT) is a new option for oral lichen planus (OLP) management; however, there are different opinions on the efficacy of PDT for OLP. The aim of this study was to comprehensively assess the...