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  1. Article

    Open Access

    Myeloid cell-specific sirtuin 6 deficiency delays wound healing in mice by modulating inflammation and macrophage phenotypes

    We recently reported that myeloid cell-expressed sirtuin 6 (Sirt6) plays a crucial role in M1 macrophage polarization and chemotaxis. Given the prominent role of macrophages during wound repair and macrophage ...

    Jeung-Hyun Koo, Hyun-Young Jang, Youngyi Lee in Experimental & Molecular Medicine (2019)

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    Article

    Inhibition of mitotic clonal expansion mediates fisetin-exerted prevention of adipocyte differentiation in 3T3-L1 cells

    Adipocytes are the key player in adipose tissue inflammation and subsequent systemic insulin resistance and its development involves complex process of proliferation and differentiation of preadipocytes. Fiste...

    Youngyi Lee, Eun Ju Bae in Archives of Pharmacal Research (2013)