-
Article
A Study on the Effects of Gendered Social Norms on the Tradeoff Between Paid and Unpaid Work in Korea
In this study, Korean time-use survey data for coupled households is analyzed to show that unpaid work time is endogenous in its relationship with paid work time because the views of traditional gender roles a...
-
Article
Open AccessSuppression of exaggerated NMDAR activity by memantine treatment ameliorates neurological and behavioral deficits in aminopeptidase P1-deficient mice
Inborn errors of metabolism (IEMs) are common causes of neurodevelopmental disorders, including microcephaly, hyperactivity, and intellectual disability. However, the synaptic mechanisms of and pharmacological...
-
Article
Open AccessThe phosphorylation status of eukaryotic elongation factor-2 indicates neural activity in the brain
Assessment of neural activity in the specific brain area is critical for understanding the circuit mechanisms underlying altered brain function and behaviors. A number of immediate early genes (IEGs) that are ...
-
Article
Aster koraiensis extract lowers postprandial glucose in normoglycemic and high-fat-diet-induced obese mice
The Aster koraiensis extract (ASKO) is a newly developed dietary herbal supplement. In this study, the potent blood glucose-lowering activity of ASKO in vitro and in vivo was investigated. In an in vitro glucose ...
-
Article
Open AccessSystemic and Local Anaphylaxis is Not Induced by Korean Red Ginseng Mixture in Guinea Pigs
Currently, injuries to customers due to health functional foods are annually increasing. To evaluate the antigenicity of Korean red ginseng mixture (KRGM), we tested for systemic anaphylactic shock and passive...
-
Article
Open AccessSeed defense biopriming with bacterial cyclodipeptides triggers immunity in cucumber and pepper
Seed priming is to expose seeds to specific compounds to enhance seed germination. Few studies of plant immune activation through seed priming have been conducted. Here, we introduce an emerging technology tha...
-
Article
Open AccessPolygonum cuspidatum inhibits pancreatic lipase activity and adipogenesis via attenuation of lipid accumulation
Obesity causes metabolic disease and is a serious health problem around the world. Polygonum cuspidatum (POCU1b) has been used clinically for the treatment of constipation, gallstones, hepatitis, and inflammation...
-
Article
Open AccessEffects of Allium victorialis leaf extracts and its single compounds on aldose reductase, advanced glycation end products and TGF-β1 expression in mesangial cells
Accumulating evidences suggest that aldose reductase (AR) inhibitors and advanced glycation end product (AGE) formation inhibitors may prevent chronic hyperglycemia-induced long-term complication in diabetes. ...
-
Article
Daldinan A, a novel isoindolinone antioxidant from the ascomycete Daldinia concentrica
-
Article
Pistillarin salt, a dicatecholspermidine family member from Gomphus floccosus, inhibits DNA single strand breakage by the fenton reaction
Pistillarin salt was isolated from the methanolic extract of Basidiomycete Gomphus floccosus. Its chemical structure was determined by various spectroscopic analyses. Pistillarin exhibited a significantly protect...
-
Article
Scopoletin from the flower buds of Magnolia fargesii inhibits protein glycation, aldose reductase, and cataractogenesis Ex Vivo
Five compounds previously known structures, scopoletin (1), northalifoline (2), stigmast-4-en-3-one (3), tiliroside (4), and oplopanone (5) were obtained from the flower buds of Magnolia fargesii using chromatogr...
-
Article
Flavonoids from Propolis Inhibit DNA Single Strand Breakage by the Fenton Reaction
Ten flavonoids were isolated from the ethanolic extract of propolis collected in the Yangpyeong of Korea. Their structures were elucidated by extensive spectroscopic methods and identified as pinostrobin, tect...
-
Article
Production of a heat-labile enterotoxin B subunit-porcine epidemic diarrhea virus-neutralizing epitope fusion protein in transgenic lettuce (Lactuca sativa)
Plant-based vaccines have been produced in transgenic plants including tobacco, potatoes, corn, and rice. However, these plants are not suitable for administration without cooking. To overcome this obstacle, a...
-
Article
Xylarinols A and B, two new 2-benzoxepin derivatives from the fruiting bodies of Xylaria polymorpha
-
Article
Expression and Assembly of Cholera Toxin B Subunit (CTB) in Transgenic Carrot (Daucus carota L.)
We expressed the cholera toxin B subunit (CTB) fused to an endoplasmic reticulum retention signal (SEKDEL) in carrot roots using an Agrobacterium-mediated transformation method. Fourteen independent transgenic li...
-
Article
Constituents of the flowers of Erigeron annuus with inhibitory activity on the formation of advanced glycation end products (AGEs) and aldose reductase
Seven phenolic compounds, caffeic acid (1), 4-hydroxybenzoic acid (2), 4-methoxybenzoic acid (3), protocatechuic acid (4), eugenol O-β-D-glucopyranoside (5), 3,6-di-O-feruloylsucrose (6), and 3,5-di-O-caffeoylqui...
-
Article
A new pancreatic lipase inhibitor isolated from the roots of Actinidia arguta
A new coumaroyl triterpene, 3-O-trans-p-coumaroyl actinidic acid (1), as well as five known triterpenes, ursolic acid (2), 23-hydroxyursolic acid (3), corosolic acid (4), asiatic acid (5) and betulinic acid (6) w...
-
Article
Inoscavin E, a Free Radical Scavenger from the Fruiting Bodies of Inonotus xeranticus
A new free radical scavenger named inoscavin E was isolated from the fruiting bodies of Inonotus xeranticus. Its structure was determined as 2-(3,4-dihydroxyphenyl)-6-[(1E)-2-(3,4-dihydroxyphenyl)ethenyl]-4H-furo...
-
Article
Xylarinic Acids A and B, New Antifungal Polypropionates from the Fruiting Body of Xylaria polymorpha
Two new polypropionates designated as xylarinic acids A and B were isolated from the fruiting body of Xylaria polymorpha. Their structures were established as 4,6,8-trimethyl-2,4-decadienoic acid and 2,4,6-trimet...
-
Article
Expression of a cholera toxin B subunit in transgenic lettuce (Lactuca sativa L.) using Agrobacterium-mediated transformation system
To increase expression level of cholera toxin B subunit (CTB) in lettuce plants, synthetic CTB (sCTB) gene based on the optimized codon usage was fused with an endoplasmic reticulum retention signal, KDEL. The...
