-
Article
Open AccessAuthor Correction: Genetic Characteristics of Korean Patients with Autosomal Dominant Polycystic Kidney Disease by Targeted Exome Sequencing
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
-
Article
Open AccessGenetic Characteristics of Korean Patients with Autosomal Dominant Polycystic Kidney Disease by Targeted Exome Sequencing
Autosomal dominant polycystic kidney disease (ADPKD) is one of the main causes of end-stage renal disease (ESRD). Genetic information is of the utmost importance in understanding pathogenesis of ADPKD. Therefo...
-
Article
Open AccessFrequent patient retraining at home reduces the risks of peritoneal dialysis-related infections: A randomised study
The present study, entitled Trial on Education And Clinical outcomes for Home PD patients (TEACH), investigated the effect of frequent retraining at home on the outcomes of peritoneal dialysis (PD). TEACH is a...
-
Article
Open AccessSerum hepcidin may be a novel uremic toxin, which might be related to erythropoietin resistance
The clinical importance of serum hepcidin in non-dialysis chronic kidney disease (CKD) patients is unclear. The database of a large-scale multicentre prospective study in Korea of 2238 patients enrolled from 2...
-
Article
Open AccessTotal kidney and liver volume is a major risk factor for malnutrition in ambulatory patients with autosomal dominant polycystic kidney disease
In patients with autosomal dominant polycystic kidney disease (ADPKD), malnutrition may develop as renal function declines and the abdominal organs become enlarged. We investigated the relationship of intra-ab...
-
Article
Association of serum adiponectin level with albuminuria in chronic kidney disease patients
Adiponectin, a peptide hormone secreted from adipocytes, exerts anti-diabetic, anti-atherogenic, and anti-inflammatory properties. We aimed to determine the relationship between serum adiponectin levels and al...
-
Chapter
Clinical Trials and a View Toward the Future of ADPKD
In light of the advances in the understanding of cystogenesis in clinical syndromes, potential therapeutic targets have been proposed. Among ciliopathies, autosomal dominant polycystic kidney disease (ADPKD) i...
-
Article
Open AccessEpigenetic silencing of the MUPCDH gene as a possible prognostic biomarker for cyst growth in ADPKD
Although autosomal dominant polycystic kidney disease (ADPKD) is a common genetic disease and is characterized by the formation of multiple fluid-filled cysts, which results in renal failure, early diagnosis a...
-
Article
Open AccessIncreased urinary Angiotensinogen/Creatinine (AGT/Cr) ratio may be associated with reduced renal function in autosomal dominant polycystic kidney disease patients
Autosomal dominant polycystic kidney disease (ADPKD) is one of the most common hereditary kidney diseases that frequently result in renal failure. In this cross-sectional observational cohort study, we evaluat...
-
Article
Open AccessIdentification of novel PKD1 and PKD2 mutations in Korean patients with autosomal dominant polycystic kidney disease
Autosomal dominant polycystic kidney disease (ADPKD) is the most common inherited kidney disorder. It is caused by mutations in the PKD1 and PKD2 genes, and manifests as progressive cyst growth and renal enlargem...
-
Article
Open AccessKNOW-CKD (KoreaN cohort study for Outcome in patients With Chronic Kidney Disease): design and methods
The progression and complications of chronic kidney disease should differ depending on the cause (C), glomerular filtration rate category (G), and albuminuria (A). The KNOW-CKD (KoreaN Cohort Study for Outcome...
-
Article
Open AccessHyperuricemia and deterioration of renal function in autosomal dominant polycystic kidney disease
The role of hyperuricemia in disease progression of autosomal dominant polycystic kidney disease (ADPKD) has not been defined well. We investigated the association of serum uric acid (sUA) with renal function ...
-
Article
Genome-wide methylation profiling of ADPKD identified epigenetically regulated genes associated with renal cyst development
Autosomal dominant polycystic kidney disease (ADPKD) is a common human genetic disease characterized by the formation of multiple fluid-filled cysts in bilateral kidneys. Although mutations in polycystic kidney d...
-
Article
Open AccessSolution-Processed Flexible Fluorine-doped Indium Zinc Oxide Thin-Film Transistors Fabricated on Plastic Film at Low Temperature
Transparent flexible fluorine-doped indium zinc oxide (IZO:F) thin-film transistors (TFTs) were demonstrated using the spin-coating method of the metal fluoride precursor aqueous solution with annealing at 200...
-
Article
Open AccessCinacalcet lowering of serum fibroblast growth factor-23 concentration may be independent from serum Ca, P, PTH and dose of active vitamin D in peritoneal dialysis patients: a randomized controlled study
Elevated serum level of fibroblast growth factor-23 (FGF23) is associated with adverse outcomes in dialyzed patients.
-
Article
Open AccessAn ‘aqueous route’ for the fabrication of low-temperature-processable oxide flexible transparent thin-film transistors on plastic substrates
Metal-oxide semiconductors have attracted considerable attention as next-generation circuitry for displays and energy devices because of their unique transparency and high performance. We propose a simple, nov...
-
Article
Open AccessChronic asymptomatic pyuria precedes overt urinary tract infection and deterioration of renal function in autosomal dominant polycystic kidney disease
Urinary tract infection (UTI) occurs in 30%-50% of individuals with autosomal dominant polycystic kidney disease (ADPKD). However, the clinical relevance of asymptomatic pyuria in ADPKD patients remains unknown.
-
Article
Sol–gel processed Cu2ZnSnS4 thin films for a photovoltaic absorber layer without sulfurization
Sol–gel processed Cu2ZnSnS4 (CZTS) thin films were fabricated without sulfurization for application as a photovoltaic absorber layer. The precursor solution was made from CuCl2, Zn(ac)2, SnCl2, thiourea, and 2-me...
-
Article
The relationship between intracranial arterial stenosis and glomerular filtration rate
Poor renal function is associated with cardiovascular complications attributable to large-vessel diseases such as arterial calcification, heart failure, myocardial infarction, and cardiac mortality. The aim of...
-
Article
Open AccessUrinary N-acetyl-β-D glucosaminidase as a surrogate marker for renal function in autosomal dominant polycystic kidney disease: 1 year prospective cohort study
Renal failure is one of the most serious complications associated with autosomal dominant polycystic kidney disease (ADPKD). To date, early markers have failed to predict renal function deterioration at the ea...
