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Open AccessProbing the existence of non-thermal Terahertz radiation induced changes of the protein solution structure
During the last decades discussions were taking place on the existence of global, non-thermal structural changes in biological macromolecules induced by Terahertz (THz) radiation. Despite numerous studies, a c...
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Article
Delta-neutrophil index: a potential predictor of coronary artery involvement in Kawasaki disease by retrospective analysis
DNI is the immature granulocyte fraction provided by a blood cell analyzer, which is determined by subtracting the fraction of mature polymorphonuclear leukocytes from the sum of myeloperoxidase-reactive cells...
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Article
Novel de novo nonsense mutation of FBN1 gene in a patient with Marfan syndrome
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Article
Palindromic assembly of the giant muscle protein titin in the sarcomeric Z-disk
The Z-disk of striated and cardiac muscle sarcomeres is one of the most densely packed cellular structures in eukaryotic cells1. It provides the architectural framework for assembling and anchoring the largest kn...
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Article
Downregulation of lipopolysaccharide response in drosophila by negative crosstalk between the AP1 and NF-κB signaling modules
IκB kinase (IKK) and Jun N-terminal kinase (Jnk) signaling modules are important in the synthesis of immune effector molecules during innate immune responses against lipopolysaccharide and peptidoglycan. Howev...
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Article
Alterations of Fas-pathway genes associated with nodal metastasis innon-small cell lung cancer
Many types of cancer cells are resistant to Fas-mediated apoptosis by several mechanisms, including the mutations of the genes involved in Fas-mediated apoptosis. In this study, to explore the possibility that...
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Article
Identification of Mad as a repressor of the human telomerase (hTERT) gene
Activation of telomerase, which has been frequently associated with cellular immortality, may constitute a key step in the development of human cancer. De-repression in the expression of its catalytic subunit ...
